Clinical characteristics of sentinel polyps and their correlation with proximal colon cancer: A retrospective observational study

Table 1 Clinical and endoscopic characteristics of the sentinel polyp group and the pure rectal polyp group, n (%)

Characteristic	Sentinel polyps	Pure rectal polyps	χ2	P value
Total number	192	2395
Gender
Male	118 (61.46)	1300 (54.28)	3.7	0.05
Female	74 (38.54)	1095 (45.72)
Age
< 40 yr old	11 (5.73)	344 (14.36)	79.1	< 0.01
40-60 yr old	64 (33.33)	1334 (55.70)
> 60 yr old	117 (60.94)	717 (29.94)
Ethnic
Uygur	44 (22.92)	631 (26.35)	1.32	0.52
Han	130 (67.71)	1525 (63.67)
Others	18 (9.37)	239 (9.98)
Anemia	58 (30.21)	206 (8.60)	90.56	< 0.01
Positivity for fecal occult blood	36 (18.75)	106 (4.43)	70.3	< 0.01
Tumor marker-positive	86 (44.79)	398 (16.62)	92.8	< 0.01
Number of polyps
1	56 (29.17)	1767 (73.78)	195.96	< 0.01
2	64 (33.33)	397 (16.58)
≥ 3	72 (37.50)	231 (9.64)
Size of polyp
< 0.5 cm	65 (33.85)	1888 (78.83)	460.46	< 0.01
0.5-1 cm	47 (24.48)	423 (17.66)
≥ 1 cm	80 (41.67)	84 (3.51)
Presence or absence of a pedicle
Pedunculated	62 (32.29)	328 (13.70)	48.01	< 0.01
Sessile	130 (67.71)	2067 (86.30)
Malignant tumors in first-degree relatives	57 (29.69)	151 (6.30)	94.726	< 0.01

Table 2 Pathological characteristics of the sentinel polyp group and the pure rectal polyp group, n (%)

Group	Adenomatous polyps				Non-adenomatous polyps
	Tubular adenoma	Villous tubular adenoma	Villous adenoma	Total	Inflamma-tory	Hyper-plastic	Juvenile	Total
Sentinel polyps	107 (55.73)	25 (13.02)	15 (7.81)	147 (76.56)a	36 (18.75)	8 (4.17)	1 (0.52)	45 (23.44)
Pure rectal polyps	898 (37.50)	46 (1.92)	24 (1.00)	968 (40.42)	1070 (44.68)	331 (13.82)	26 (1.08)	1427 (59.58)

^aP < 0.01 vs pure rectal polyp group.