Distribution and drug resistance of pathogenic bacteria in emergency patients

Table 1 Analysis of resistance rates of Gram-negative bacteria

Gram-negative bacteria	Drugs	2013		2014		2015		2016		2017		CATT	P value
		R	I/S	R	I/S	R	I/S	R	I/S	R	I/S
Acinetobacter baumannii	Cefoperazone/sulbactam	84	97	91	86	79	15	80	23	80	25	47.72	< 0.01
	Imipenem	174	7	170	7	89	5	97	6	102	3	0.05	0.82
	Tigecycline	7	174	6	171	0	94	10	93	12	93	11.13	< 0.01
	Amikacin	91	90	89	89	-	-	-	-	-	-	0.00	1.00
	Ciprofloxacin	171	10	167	10	89	5	98	5	103	2	1.46	0.23
	Minocycline	116	65	70	107	17	77	29	74	15	90	79.13	< 0.01
Pseudomonas aeruginosa	Cefoperazone/sulbactam	18	69	17	58	7	49	19	39	27	35	10.17	< 0.01
	Imipenem	29	58	39	36	28	28	28	30	24	38	0.31	0.58
	Tigecycline	-	-	-	-	-	-	-	-	-	-	-	-
	Amikacin	5	82	5	70	2	54	5	53	2	60	0.06	0.80
	Ciprofloxacin	19	68	20	55	16	40	15	44	10	52	0.47	0.50
	Minocycline	-	-	-	-	-	-	-	-	-	-	-	-
Klebsiella pneumoniae	Cefoperazone/sulbactam	12	39	58	30	23	41	33	38	40	33	1.94	0.16
	Imipenem	5	46	54	34	25	39	32	39	34	39	3.91	0.05
	Tigecycline	-	-	6	82	5	59	12	59	7	66	1.48	0.22
	Amikacin	1	50	36	52	19	45	28	43	25	48	6.86	< 0.01
	Ciprofloxacin	20	31	58	30	35	29	35	36	40	33	0.04	0.85
	Minocycline	23	28	31	57	19	45	13	58	12	61	17.53	< 0.01
Escherichia coli	Cefoperazone/sulbactam	3	51	2	37	12	45	4	44	13	26	11.30	< 0.01
	Imipenem	0	54	4	35	3	54	0	48	5	34	3.21	0.07
	Tigecycline	-	-	3	36	0	57	0	48	0	39
	Amikacin	3	51	1	38	1	56	1	47	7	32	3.20	0.07
	Ciprofloxacin	35	19	25	14	34	23	28	20	27	12	0.00	0.98
	Minocycline	19	35	7	32	4	53	9	39	4	35	8.41	< 0.01

S: Sensitive; I: Intermediate resistant; R: Resistant.

Table 2 Analysis of resistance rates of Gram-positive bacteria

Gram-positive bacteria	Drugs	2013		2014		2015		2016		2017		CATT	P value
		R	I/S	R	I/S	R	I/S	R	I/S	R	I/S
Staphylococcus aureus	Vancomycin	0	149	0	142	0	58	0	44	0	43	-	-
	Levofloxacin	131	18	130	12	38	20	25	19	21	22	53.68	< 0.01
	Linezolid	1	148	4	138	0	58	0	44	0	43	0.75	0.39
	Tigecycline	0	149	0	142	0	58	0	44	0	43	-	-
	PenicillinG	146	3	140	2	55	3	41	3	41	2	3.45	0.06
	Tetracycline	123	26	131	11	35	23	26	18	25	18	28.27	< 0.01

Table 3 Analysis of clinical data of patients with Klebsiella pneumoniae infection (n = 347)

Influence factors		Cases	Percentage (%)	Influence factors		Cases	Percentage (%)
Gender	Male	175	53.19	Deep vein catheterization	Yes	224	68.09
	Female	154	46.81		No	105	31.91
Age (yr)	≥ 60	277	84.19	Mechanical ventilation	Yes	93	28.27
	< 60	52	15.81		No	236	71.73
Tracheotomy	Yes	9	2.74	Retention catheterization	Yes	241	73.25
	No	320	97.26		No	88	26.75