Longitudinal observation of ten family members with idiopathic basal ganglia calcification: A case report

Table 1 The changes in mini mental state examination and revised hasegawa dementia scale scores of the proband

Age	MMSE	HDS-R
65 yr	19	20
66 yr	21	20
67 yr	23	16
69 yr	21	13
71 yr	19	12
74 yr	19	12
75 yr	Disordered consciousness	Disordered consciousness
76 yr	Disordered consciousness	Disordered consciousness

MMSE: Mini mental state examination; HDS-R: Revised hasegawa dementia scale.

Table 2 Demographic information, clinical features, and instrumental data for all patient

Patient	Age at examination	Sex	Clinical features	Localization of brain calcification			Mutation
				Striatum	Pallidum	Cerebellar dentate nuclei
II-1	69	F	Dementia, Irritability and agression	-	+	-	SLC20A2 (c.344C>T)
II-5	61	F	Asymptomatic (only headache)	-	+	-	SLC20A2 (c.344C>T)
II-7	59	M	Mental retardation	-	+	-	SLC20A2 (c.344C>T)
II-8	58	M	Alcoholism	+	-	-	SLC20A2 (c.344C>T)
II-9	56	F	Asymptomatic	-	+	-	SLC20A2 (c.344C>T)
III-1	49	M	Adjustment disorder	+	+	-	SLC20A2 (c.344C>T)
III-2	44	F	Asymptomatic	-	-	-	-
III-3	36	F	Panic disorder	+	+	-	SLC20A2 (c.344C>T)
III-5	18	M	Asymptomatic	-	-	-	-
IV-1	8	F	Asymptomatic	-	-	-	-