Effect of Helicobacter pylori eradication on elder cases: Observational study in community-based medicine

Table 1 Comparison of various factors before and after Helicobacter pylori eradication therapy in all subjects (n = 130)

Variable	Subjects	Missing	Pre-eradication mean (SD)	Post-eradication mean (SD)	Mean difference	95%CI	P value
Body weight (kg)	124	6	57.3 (10.4)	58.2 (10.3)	0.52	0.09-0.94	0.018
BMI (kg/m2)	121	9	23.4 (3.1)	23.7 (3.0)	0.25	0.074-0.42	0.006
Hb (g/dL)	115	15	13.8 (1.4)	13.8 (1.3)	0.018	-0.35	0.84
MCV (fL)	113	17	89.2 (4.9)	90 (4.4)	0.83	0.32-1.34	< 0.001
TP (g/dL)	90	40	7.4 (0.5)	7.5 (0.4)	0.024	-0.168	0.56
LDL-C (mg/dL)	107	23	114.3 (23.9)	116.2 (25.0)	1.20	-8.12	0.55
TG (mg/dL)	107	23	122 (70.5)	126.6 (77.1)	6.81	-22.59	0.23
HbA1c (%)	42	88	6.2 (0.81)	6.3 (0.75)	0.057	-0.305	0.45

BMI: Body mass index; Hb: Haemoglobin; MCV: Mean corpuscular volume; TP: Total protein; LDL-C: Low-density lipoprotein cholesterol; TG: Triglyceride; HbA1c: Haemoglobin A1c.

Table 2 Subgroup analysis of various factors before and after Helicobacter pylori eradication therapy in the group of patients > 65 years (n = 97)

Variable	Subjects	Missing	Pre-eradication mean (SD)	Post-eradication mean (SD)	Mean difference	95%CI	P value
Body weight (kg)	92	5	57.1 (10.4)	57.8 (10.3)	0.41	-1.017	0.12
BMI (kg/m2)	90	7	23.6 (3.0)	23.8 (3.1)	0.21	-0.4159	0.045
Hb (g/dL)	85	12	13.7 (1.5)	13.7 (1.3)	-0.02	-0.4	0.84
MCV (fL)	85	12	89.2 (5.3)	90.1 (4.7)	0.95	-1.17	0.0017
TP (g/dL)	66	31	7.5 (0.5)	7.5 (0.4)	0.011	-0.216	0.84
LDL-C (mg/dL)	77	20	111.9 (21.2)	114.2 (24.8)	1.25	-9.65	0.61
TG (mg/dL)	77	20	116.7 (56.2)	112.6 (44.8)	-1.68	-20.35	0.74
HbA1c (%)	30	67	6.4 (0.8)	6.4 (0.7)	0.013	-0.35	0.88

BMI: Body mass index; Hb: Haemoglobin; MCV: Mean corpuscular volume; TP: Total protein; LDL-C: Low-density lipoprotein cholesterol; TG: Triglyceride; HbA1c: Haemoglobin A1c.

Table 3 Differences in the eradication effect on the rate of increase in haemoglobin level between groups of patients with < haemoglobin 12.5 g/dL (n = 20) and patients with ≥ haemoglobin 12.5 g/dL (n = 96)

Variable	Subjects	Missing	Pre-eradication mean (SD)	Post-eradication mean (SD)	Mean difference	95%CI	P value
Less than Hb 12.5 g/dL	19	1	11.5 (0.7)	12.3 (1.0)	0.85	0.22-1.48	0.017
More over Hb 12.5 g/dL	96	11	14.2 (1.1)	14.1 (1.2)	-0.15	-0.1592	0.064

Hb: Haemoglobin.