Sweet syndrome and differentiation syndrome in a patient with acute promyelocytic leukemia

Table 1 Cases of sweet syndrome associated with differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid

Ref.	Age(yr)/sex	Cutaneous location	Biopsy	Onset of skin lesions after ATRA induction therapy (d)	Onset of the DS after ATRA induction therapy (d)	DS signs and symptoms	Steroid response	Time until improvement
Takada et al[5]	49/F	Arms	Yes	18	28	Respiratory distress	Yes	24 h
Astudillo et al[2]	46/M	Trunk, arms, lower extremities	Yes	6	uk	Weight gain	Yes	Unknown
This case	50/M	Trunk lower extremities	Yes	21	25	Respiratory distress Hypotension	Yes	48 h

DS: Differentiation syndrome; ATRA: All-trans retinoic acid; M: Male; F: Female.