Upper esophageal sphincter abnormalities are strongly predictive of treatment response in patients with achalasia

Table 1 Distribution of upper esophageal sphincter abnormality by achalasia sub-type

Type of achalasia	UES abnormality			P-value
	Hypertensive (%)	Hypotensive (%)	Impaired relaxation (%)
Type I	22.22	50	0.00	0.3345
Type II	55.56	50	85.71
Type III	22.22	0	14.29

UES: Upper esophageal sphincter.

Table 2 Type of treatment received based on upper esophageal sphincter abnormality sub-type

Treatment	UES abnormality			P-value
	Hypertensive (%)	Hypotensive (%)	Impaired relaxation (%)
Pneumatic dilatation	0	25	11.11	0.3967
Endoscopic botox treatment	25	0	22.22
Medical therapy	0	0	22.22
POEM	12.5	0	11.11
Surgical myotomy	62.5	75	33.33

UES: Upper esophageal sphincter.

Table 3 Treatment response based on presence of upper esophageal sphincter abnormality

Treatment response	No UES abnormality	UES abnormality	P-value
Favorable	78.57%	12.50%	< 0.0001
Poor	21.43%	87.50%

UES: Upper esophageal sphincter.