Simultaneous vs staged treatment of urolithiasis in patients undergoing radical prostatectomy

Table 1 Patient demographics n (%)

	Simultaneous(n = 10)	Staged(n = 12 )	P-value
Age (yr), median (IQR)	68 (60-71)	63 (62-67)	0.41
Stone size (mm), mean ± SD	8.0 ± 3.8	9.9 ± 5.3)	0.31
Location
Renal	2 (20)	2 (17)	0.82
Proximal	2 (20)	2 (17)	0.82
Multiple	1 (10)	4 (33)	0.22
Distal	5 (50)	4 (33)	0.42
Procedure (n = 29)	11	18
Open	2 (18)	0 (0)	-
Rigid URS	5 (46)	5 (28)	-
Flexible URS	2 (18)	4 (22)	-
SWL	2 (18)	4 (22)	-
PCNL	0 (0)	5(28)	-
RARP	1 (10)	2 (17)	-
RRP	9 (90)	10 (83)	-
Patient symptomatic	7 (70)	10 (83)	0.53
History of stones	9 (90)	7 (58)	0.13

¹Student’s t-test;

²Fisher’s Exact;

³χ². IQR: Interquartile range; SD: Standard deviation; SWL: Shock wave lithotripsy; URS: Ureteroscopy; PCNL: Percutaneous nephrolithotomy; RARP: Robot assisted radical prostatectomy; RRP: Radical retropubic prostatectomy.

Table 2 Simultaneous vs staged urinary stone treatment at time of prostatectomy n (%)

	Simultaneous(n = 10)	Staged(n = 12)	P-value
Patient complications	3 (30)	5 (42)	0.61
Steinstrasse	0 (0)	2 (17)	0.21
Bleeding2	2 (20)	4 (33)	0.51
AKI	0 (0)	1 (8)	0.41
Urosepsis	1 (10)	0 (0)	0.31
BNC	2 (20)	1 (8)	0.41
Urinary incontinence	2 (33)	5 (42)	0.71
Change in Cr (mg/dL), mean ± SD	0.04 ± 0.2	-0.2 ± 0.5	0.13
change in Hb (g/dL), mean ± SD	3.9 ± 1.4	4.7 ± 1.6	0.23
Hospital (d), mean ± SD	4.5 ± 3.8	5.5 ± 2.8	0.53
Stone free	6 (60)	7 (58)	0.94
Multiple procedures	1 (10)	4 (33)	0.24
Avg. # stone procedures, mean ± SD	1.1 ± 0.3	1.4 ± 0.7	0.23

¹Fisher’s Exact;

²Occurred at the time of prostatectomy;

³Student’s t-test;

⁴χ². BNC: Bladder neck contracture; AKI: Acute kidney injury; Cr: Creatinine; Hb: Hemoglobin; SD: Standard deviation.

Table 3 Simultaneous vs staged ureteroscopic stone treatment at time of prostatectomy n (%)

	Simultaneous(n = 6)	Staged(n = 7)	P-value
Age (yr), median (IQR)	70 (65-71)	63 (61-68)	0.061
Patient complications	1 (17)	3 (43)	0.32
Steinstrasse	0 (0)	0 (0)	-
Bleeding3	1 (17)	3 (43)	0.32
AKI	0 (0)	1 (14)	0.32
BNC	0 (0)	1 (14)	0.32
Urinary Incontinence	2 (40)	3 (43)	0.92
Change in Cr (mg/dL), mean ± SD	0.04 ± 0.1	-0.4 ± 0.5	0.14
Change in Hb (g/dL), mean ± SD	4.1 ± 1.8	5.1 ± 0.9	0.24
Hospital (d), mean ± SD	2.8 ± 2.1	5.5 ± 3.5	0.14
Multiple procedures	1 (17)	1 (14)	0.94
Avg. # stone procedures, mean ± SD	1.2 ± 0.4	1.1 ± 0.4	0.94
Stone free	4 (67)	6 (86)	0.44
Stone size (mm), mean ± SD	5.8 ± 1.7	6.9 ± 2.3	0.34

¹Student’s t-test;

²Fisher’s Exact;

³Occurred at the time of prostatectomy;

⁴χ². BNC: Bladder neck contracture; AKI: Acute kidney injury; Cr: Creatinine; Hb: Hemoglobin; SD: Standard deviation.

Table 4 Simultaneous vs staged SWL at time of prostatectomy n (%)

	Simultaneous(n = 2)	Staged(n = 4)	P-value
Age (yr), median (IQR)	55 (53-57)	63 (62-65)	0.11
Patient complications	1 (50)	3 (75)	0.52
Steinstrasse	0 (0)	2 (50)	0.22
Bleeding3	0 (0)	2 (50)	0.22
AKI	0 (0)	0 (0)	-
Urosepsis	1 (50)	0 (0)	0.12
BNC	0 (0)	0 (0)	-
Urinary incontinence	-	1 (25)	-
Change in Cr (mg/dL), mean ± SD	0.15 ± 0.4	-0.3 ± 0.3	0.41
Change in Hb (g/dL), mean ± SD	3.9 ± 0.8	5.1 ± 1.7	0.51
Hospital (d), mean ± SD	4.0 ± 1.4	4.8 ± 1.5	0.61
Multiple procedures	0	3 (75)	0.082
Avg. # stone procedures, mean ± SD	1.0 (0.0)	2.0 (0.8)	0.21
Stone free	2 (100)	1 (25)	0.082
Stone size (mm), mean ± SD	12.5 ± 6.4	10.4 ± 1.3	1.01

¹Wilcoxon Rank Sum;

²Fisher’s Exact;

³Occurred at the time of prostatectomy. BNC: Bladder neck contracture; AKI: Acute kidney injury; Cr: Creatinine; Hb: Hemoglobin.