Wang XY, Hao Y, Wang ZJ, Xu XL, Yang JH. Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis: A retrospectively study of past ten years. World J Clin Cases 2025; 13(2): 96557 [DOI: 10.12998/wjcc.v13.i2.96557]
Corresponding Author of This Article
Jiang-Hua Yang, BMed, Chief Doctor, Full Professor, Department of Infectious Diseases, The First Affiliated of Wannan Medical College, No. 2 Zheshan West Road, Yijishan Street, Jinghu District, Wuhu 241001, Anhui Province, China. yjhpath@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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World J Clin Cases. Jan 16, 2025; 13(2): 96557 Published online Jan 16, 2025. doi: 10.12998/wjcc.v13.i2.96557
Table 1 Proportion of schistosomal appendicitis in total appendicitis treated in the First Affiliated Hospital of Wannan Medical College from October 2013 to October 2023
Date
SA group (n)
NSA group (n)
SA proportion (%)
October 2013 to October 2014
11
495
2.20
October 2014 to October 2015
16
537
2.90
October 2015 to October 2016
9
487
1.80
October 2016 to October 2017
11
572
1.90
October 2017 to October 2018
20
565
3.40
October 2018 to October 2019
17
535
3.10
October 2019 to October 2020
11
568
1.90
October 2020 to October 2021
8
507
1.60
October 2021 to October 2022
17
555
3.00
October 2022 to October 2023
16
597
2.60
Table 2 Analysis of general data and pathological types of schistosomal appendicitis and non schistosomal appendicitis, n (%)
Group
SA group (n = 136)
NSA group (n = 5418)
χ2/Z
P value
Gender
40.753
< 0.001
Female
42 (30.1)
2601 (48)
Male
94 (69.9)
2818 (52)
Age, mean ± SD (years)
61.73 ± 15.335
35.8 ± 24.013
-12.722
< 0.001
Classification
33.234
< 0.001
Acute simple appendicitis
12 (8.8)
677 (12.6)
Acute suppurative appendicitis
42 (39.8)
2546 (47.2)
Gangrenous or perforated appendicitis
37 (27.2)
1303 (24.2)
Periappendicular abscess
0 (0)
2 (0)
Acute attack of chronic appendicitis
45 (33.1)
862 (16)
Table 3 Acute simple appendicitis
β
SE
Wald
P value
95%CI
Schistosomal appendicitis
-0.389
0.305
1.626
0.202
0.678 (0.373-1.232)
Table 4 Acute suppurative appendicitis
β
SE
Wald
P value
95%CI
Schistosomal appendicitis
-0.685
0.188
13.34
< 0.001
0.504 (0.349-0.728)
Table 5 Gangrenous or perforated appendicitis
β
SE
Wald
P value
95%CI
Schistosomal appendicitis
0.166
0.195
0.721
0.396
1.180 (0.805-1.731)
Table 6 Periappendicular abscess
β
SE
Wald
P value
95%CI
Schistosomal appendicitis
-13.299
3446.519
0
0.977
0 (0)
Table 7 Acute attack of chronic appendicitis
β
SE
Wald
P value
95%CI
Schistosomal appendicitis
0.961
0.186
26.684
< 0.001
2.614 (1.815-3.763)
Table 8 Analysis of general situation and past history of patients with schistosomal appendicitis and non schistosomal appendicitis, n (%)
Group
SA group (n = 136)
NSA group (n = 136)
χ2/Z
P value
Gender
8.15
0.004
Female
42 (30.9)
65 (47.8)
Male
94 (69.1)
71 (52.2)
Age, mean ± SD (years)
61.73 ± 15.335
33.21 ± 22.974
-9.519
< 0.001
Smoking history
9 (7.5)
6 (4.4)
1.102
0.294
Drinking history
7 (5.8)
1 (0.7)
3.919
0.048
Hypertension history
16 (13.3)
10 (7.4)
2.499
0.114
Coronary heart disease history
9 (7.5)
5 (3.7)
1.803
0.179
Diabetes history
2 (1.7)
2 (1.7)
0
1
Table 9 Analysis of clinical symptoms and complications of schistosomal appendicitis and non schistosomal appendicitis, n (%)
Group
SA group (n = 136)
NSA group (n = 136)
χ2/Z
P value
Fever
1 (0.8)
6 (4.4)
1.871
0.171
Nausea and vomiting
30 (25)
36 (26.5)
0.072
0.788
Abdominal pain
106 (88.3)
125 (91.9)
0.926
0.336
Diarrhea
0
1 (0.7)
0
1
Constipation
2 (1.7)
1 (0.7)
0.012
0.913
Peritonitis
76 (63.3)
83 (61)
0.144
0.705
Colorectal cancer
14 (11.7)
3 (2.2)
9.204
0.002
Table 10 Colorectal cancer
β
SE
Wald
P value
95%CI
Schistosomal appendicitis
1.627
0.648
6.294
0.012
5.087 (1.427-18.132)
Table 11 Analysis of laboratory examination of schistosomal appendicitis and non schistosomal appendicitis, mean ± SD
Group
SA group (n = 136)
NSA group (n = 136)
Z/t
P value
WBC (109/L)
10.142 ± 3.638
9.382 ± 3.637
-2.033
0.042
RBC (1012/L)
3.432 ± 0.645
3.949 ± 0.587
-6.28
< 0.001
NEU (109/L)
8.691 ± 4.217
7.288 ± 3.3
-2.95
0.003
LYM (109/L)
1.185 ± 0.558
0.921 ± 0.492
-3.544
< 0.001
MO (109/L)
0.696 ± 0.366
0.571 ± 0.283
-2.68
0.007
EO (109/L)
0.115 ± 0.127
0.057 ± 0.283
-4.428
< 0.001
BA (109/L)
0.003 ± 0.018
0.01 ± 0.032
-1.83
0.067
HGB (g/L)
116.02 ± 16.829
120.81 ± 15.978
2.336
0.020
PLT (109/L)
196.40 ± 87.267
202.96 ± 67.237
-1.046
0.295
HCT
0.344 ± 0.048
0.358 ± 0.061
-2.045
0.041
TP (g/L)
61.839 ± 6.703
62.909 ± 6.57
1.154
0.250
ALB (g/L)
33.719 ± 5.279
36.515 ± 5.635
3.657
< 0.001
ALT (U/L)
19.13 ± 15.389
20.08 ± 16.346
-0.66
0.509
AST (U/L)
19.258 ± 8.855
22.184 ± 15.582
-1.789
0.074
Cr (μmol/L)
61.785 ± 16.525
56.303 ± 19.990
-0.679
0.498
Bun (μmol/L)
5.316 ± 4.435
4.807 ± 3.120
-2.204
0.028
UA (μmol/L)
274.439 ± 84.443
265.027 ± 96.503
-0.717
0.414
TC (mmol/L)
3.775 ± 0.776
21.747 ± 95.122
-1.192
0.233
TG (mmol/L)
1.164 ± 0.516
1.245 ± 0.560
-0.506
0.613
C-reactive protein (mg/L)
60.932 ± 46.672
61.546 ± 45.350
-0.443
0.658
PCT (ng/L)
1.15
0.273 ± 0.118
-1.414
0.4
Citation: Wang XY, Hao Y, Wang ZJ, Xu XL, Yang JH. Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis: A retrospectively study of past ten years. World J Clin Cases 2025; 13(2): 96557