Genetic disorders leading to severe hyperlipidemia in children: A case report

Table 1 Liver function indexes, blood lipids and drug therapy (The liver function tests and cholesterol were improved after Chinese medicine treatment)

Age	ALT (IU/L) (0-40)	AST (IU/L) (0-40)	GGT (IU/L) (7-32)	TBIL (IU/L) (5.13-22.24)	DBIL (IU/L) (1.7-10.2)	TC mmol/L (2.83-5.2)	LDLC mmol/L (2.07-3.37)	ALP (IU/L) (50-135)	Medicine
50 days	530	773	1362	54.6	34.4	15.38	/	1203	Compound glycyrrhizin, Yin lotus clear liver particles
2 years and 10 months	186	148	643	24.3	16.3	16.93	14.0	487	Vitamin B, vitamin C, polyene phosphatidylcholi-ne, ursodeoxycholic acid
11 years and 7 months	200	116	682	/	/	12.08	4.81	497	Drug withdrawal
11 years and 8 months	77	64	264	/	/	9.28	5.54	115	Ursodeoxycholic acid, vitamin B, Traditional Chinese medicine preparation
11 years and 9 months	151	77	597	16.8	8.7	8.7	5.29	124	Membrane of Chickens Gizzard

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transferase; TBIL: Total bilirubin; DBIL: Direct bilirubin; TC: Total cholesterol; LDLC: Low-density lipoprotein cholesterol; ALP: Alkaline phosphatase.

Table 2 Changes in body composition analysis pretherapy and post-treatment.

Body composition	11 years and 6 months	11 years and 8 months	Normal range
Total body water (L)	20.2	20.7	22.3-27.3
Protein (kg)	5.3	5.6	6.0-7.4
Inorganic salt (kg)	2.14	2.14	2.07-2.53
Body fat (kg)	8.4	10.3	7.2-14.4
Weight (kg)	36.04	38.7	36.4-49.2

Table 3 Dosage of Chinese medicines treatment for the patient

Age	Name of Chinese medicine	Dosages	Name of Chinese medicine	Dosages	Name of Chinese medicine	Dosages	Name of Chinese medicine	Dosages
11 years and 8 months	Radix; Bupleuri	10 g	Aurantii; Fructus; Immaturus	10 g	Stir-fried; Atractylodes macrocephala; Koidz	12 g	Poria	20 g
	Ligusticum chuanxiong; Hort	10 g	Angelica sinensis	15 g	Chinese Hawthorn Fruit (charred	15 g	Burnt malt	15 g
	Dried orange peel used in Chinese medicine	10 g	Paeonia lactiflora	10 g	Glycyrrhiza uralensis; Fisch	3 g
11 years and 9 months	Membrane of Chickens Gizzard	5g (take it with lunch)