Imaging, pathology, and diagnosis of solitary fibrous tumor of the pancreas: A case report and review of literature

Table 1 Characteristics of pancreatic solitary fibrous tumors

No	Ref.	Age	Sex	Pancreatic site	Symptoms	Size (cm)	Pancreatic surgery
1	Lüttges et al[1]	50	F	Body	Incidental	55	DP
2	Chatti et al[8]	41	M	Body	Abdominal pain	13	DP
3	Gardini et al[9]	62	F	Head	Abdominal pain	3	PD
4	Miyamoto et al[10]	41	F	Head	Abdominal pain	18 × 15	Enucleation
5	Kwon et al[11]	54	M	Body	Incidental	76 × 6	MS
6	Srinivasan et al[12]	78	F	Body	Back pain, weight loss	5	DP
7	Chetty et al[13]	67	F	Head	Incidental	26	PD
8	Ishiwatari et al[14]	58	F	Head	Incidental	3	PD
9	Sugawara et al[15]	55	F	Head	Incidental	6 × 4	PD
10	Santos et al[16]	40	M	Body	Incidental	3	Enucleation
11	Tasdemir et al[17]	24	F	Body	Epigastric pain	11	Enucleation
12	van der et al[18]	67	F	Head	Abdominal pain	28 × 16	Enucleation
13	Chen et al[19]	49	F	Head	Abdominal pain	13	PD
14	Hwang et al[20]	53	F	Head	Incidental	52 × 45 × 40	PHR
15	Baxter et al[21]	58	F	Head	Abdominal pain	35 × 3	LPD
16	Estrella et al[22]	52	F	Head	Jaundice	15 × 10 × 10	LPD
17	Han et al[23]	77	F	Head	Jaundice	15 × 14	Biopsy
18	Murakami et al[24]	82	M	Body	Hypokalemia hypertension, edema	6	DP
19	Spasevska et al[3]	47	M	Head	jaundice	35 × 2 × 18	LPD
20	Paramythiotis et al[7]	55	M	Body	Abdominal pain	31 × 28	DP
21	D'Amico FE et al[25]	52	M	Body	Incidental	12	DP
22	Oana et al[26]	73	M	Head	Abdominal discomfort	65 × 55	Enucleation
23	Sheng et al[27]	1	M	Head	Jaundice	20	DP
24	Geng et al[28]	48	M	Body	Hypoglycemia	65 × 5	DP
25	Qian et al[29]	46	M	Body	Hypoglycemia	70 × 61	DP
26	Rogers et al[30]	37	F	Head	Abdominal pain	23	PD
27	Taguchi et al[31]	60	M	Head	Palpable mass	9 × 7 × 7	PD
28	Jariwalla et al[32]	64	F	Body	Abdominal pain	19	DP
29	Marotti et al[33]	75	F	Body	Incidental	13	Enucleation
30	Addeo et al[6]	59	M	Body	Incidental	4	DP
31	Rodriguez et al[2]	48	F	Body	Abdominal pain	13 × 10 × 95	TP
32	Jones et al[34]	61	F	Body	NA	27	DP
33	Liu et al[35]	54	F	Head	Incidental	31 × 23	LDPPHRt
34	Present case	54	M	Body	Incidental	3 × 2	DP

LDPPHRt: Laparoscopic duodenum-preserving pancreatic head resection; Ms: median segmentectomy; PHR: Pancreatic head resection; TP: Total pancreatectomy; PD: Pancreaticoduodenectomy; DP: Distal pancreatectomy.

Table 2 Histological features and outcomes of pancreatic solitary fibrous tumors

No	Ref.	Immunohistochemistry	Outcome	Follow-up
1	Lüttges et al[1]	CD34, CD99, Bcl-2, vimentin	Alive	20 months
2	Chatti et al[8]	CD34, CD99, Bcl-2, vimentin	Death	3 d
3	Gardini et al[9]	CD34, CD99, Bcl-2, vimentin, SMA	Alive	16 months
4	Miyamoto et al[10]	CD34, Bcl-2	Alive	7 months
5	Kwon et al[11]	CD34, CD99, vimentin	NA	NA
6	Srinivasan et al[12]	CD34, Bcl-2	Alive	7 months
7	Chetty et al[13]	CD34, CD99, Bcl-2	42 mo	6 v
8	Ishiwatari et al[14]	CD34, Bcl-2	Alive	42 months
9	Sugawara et al[15]	CD34	NA	NA
10	Santos et al[16]	CD34, betacatenin	NA	NA
11	Tasdemir et al[17]	CD34, Bcl-2, beta-catenin, vimentin, Ki67 < 2%	Alive	3 months
12	van der et al[18]	CD34, CD99, Bcl-2	NA	NA
13	Chen et al[19]	CD34, Bcl-2, vimentin, CD68, muscle-specific actin	Alive	30 months
14	Hwang et al[20]	CD34, Bcl-2, muscle-specific actin, CD10, ER, PR	Alive	30 months
15	Baxter et al[21]	CD34, Bcl-2	NA	NA
16	Estrella et al[22]	CD34, Bcl-2, keratin (rare), p16, p53	Alive	40 months
17	Han et al[23]	CD34, CD99	No progression	10 months
18	Murakami et al[24]	STAT6, CD34, Bcl-2, ACTH, POMC, NSE	Death	4 months
19	Spasevska et al[3]	CD34, vimentin, CD99, Bcl-2, nuclear betacatenin	Death	1 wk
20	Paramythiotis et al[7]	CD34, CD99, Bcl-2 vimentin, S-100	Alive	40 months
21	D'Amico FE et al[25]	STAT6, CD34	Alive	24 months
22	Oana et al[26]	CD34, Bcl-2	Alive	36 months
23	Sheng et al[27]	CD34, vimentin, SMA, Ki67 < 3%	Alive	12 months
24	Geng et al[28]	STAT6, CD34, Bcl-2, CD31, PHH-3, D2-40, Ki67 > 10%	Alive	6 months
25	Qian et al[29]	STAT6, CD34, Bcl-2, Ki67 10%	Alive	10 months
26	Rogers et al[30]	STAT6, CD34, Bcl-2, CD99	Alive	4 months
27	Taguchi et al[31]	STAT6, CD34, Bcl-2, vimentin, cytokeratin AE1/AE3	Alive	12 months
28	Jariwalla et al[32]	STAT6, CD34	NA	NA
29	Marotti et al[33]	STAT6, CD34	Alive	6 months
30	Addeo et al[6]	STAT6, CD34, Bcl-2, Ki67 7%	NA	NA
31	Rodriguez et al[2]	STAT6	Alive	12 months
32	Jones et al[34]	STAT6, CD34	Alive	1 months
33	Liu et al[35]	CD34, STAT6, CD99	Alive	6 months
34	Present case	TAT6, CD34, Bc1-2, Vimentin, CD99, Ki67 40%	Alive	3 months

STAT6: Signal transducer and activator of transcription 6; ER: Estrogen receptor; PR: Progesterone receptor; SMA: Smooth muscle actin; NA: Not applicable.