Risk factors and risk prediction model for mucocutaneous separation in enterostomy patients: A single center experience

Table 1 Clinicopathological characteristics, n (%)

Variable	Non-MCS (n = 382)	MCS (n = 110)	P value
Sex			0.4106
Male	241 (63.1)	64 (58.2)
Female	141 (36.9)	46 (41.8)
Age (years)
< 60	115 (30.1)	35 (31.8)	0.8209
≥ 60	267 (69.9)	75 (68.25)
Intestinal rapture	14 (3.7)	12 (10.95)	0.0059
Diabetic	89 (23.3)	26 (23.6)	1.0000
Immunotherapy	153 (40.0)	45 (40.9)	0.9592
Neoadjuvant therapy	153 (40.0)	56 (50.9)	0.0548
Suture dislodgement	42 (11.0)	63 (57.3)	< 0.0001
Incision infection	49 (12.8)	42 (38.2)	< 0.0001
BMI (kg/m2)
< 24	257 (67.3)	54 (49.1)	0.0007
≥ 24	125 (32.7)	56 (50.9)
Stoma site
Ileum	228 (59.7)	83 (75.4)	0.0036
Colon	154 (40.3)	27 (24.6)
Elevated intra-abdominal pressure	183 (47.9)	65 (59.1)	0.0501
Hemoglobin level
≤ 90	82 (21.5)	34 (30.9)	0.0501
> 90	300 (78.5)	76 (69.1)
Albumin level
≤ 28	54 (14.1)	34 (30.9)	< 0.0001
> 28	328 (85.9)	76 (69.1)

BMI: Body mass index; MCS: Mucocutaneous separation.

Table 2 Univariate and multivariate analysis

Variable	Univariate, P value	Multivariate, P value	OR	95%CI
				Lower	Upper
Suture dislodgement	< 0.0001	< 0.0001	28.0075	11.0901	82.1751
Serum albumin	< 0.0001	0.0008	0.3504	0.1902	0.6485
BMI	0.0006	0.0045	2.1361	1.2660	3.6235
Hemoglobin	0.0409	0.0269	0.5164	0.2881	0.9324
Intestinal rapture	0.0043	0.0351	3.0694	1.0482	8.5558
Incision infection	< 0.0001	0.0179	0.2885	0.0950	0.7624
Neoadjuvant therapy	0.0432	0.0112	1.9769	1.1718	3.3690
Stoma site	0.0028	0.1996	0.6908	0.3881	1.2071
Elevated intra-abdominal pressure	0.0395	0.1194	1.5162	0.2881	0.9324
Diabetic	0.9412	-	-	-	-
Age	0.7309	-	-	-	-
Immunotherapy	0.8717	-	-	-	-
Sex	0.3506	-	-	-	-

BMI: Body mass index.