Clinical and Translational Research
Copyright ©The Author(s) 2024.
World J Clin Cases. Sep 6, 2024; 12(25): 5729-5738
Published online Sep 6, 2024. doi: 10.12998/wjcc.v12.i25.5729
Table 1 Mendelian randomization estimates from different methods of assessing the causal effect between the ratio of cholesterol to total lipids in medium very-low-density lipoprotein and peptic ulcer
Exposure
Outcome
Method
Nsnp
OR (95%CI)
P value
Ratio of cholesterol to total lipids in medium VLDLPeptic ulcerIVW722.557 (1.274-5.132)0.008
WM722.106 (0.709-6.252)0.179
  MR Egger 726.394 (1.958-20.878)0.003
Table 2 Heterogeneity and pleiotropy tests of the Mendelian randomization analysis
Exposure/Outcome
Heterogeneity test
Multi-efficiency test
MR Egger, IV
MR Egger
Q
P value
Q
P value
Intercept
P value
Ratio of cholesterol to total lipids in medium VLDL/peptic ulcer59.9190.68763.4480.6-0.0610.064