Gao ZY, Peng WL, Li Y, Lu XH. Hounsfield units in assessing bone mineral density in ankylosing spondylitis patients with cervical fracture-dislocation. World J Clin Cases 2024; 12(23): 5329-5337 [PMID: 39156086 DOI: 10.12998/wjcc.v12.i23.5329]
Corresponding Author of This Article
Xu-Hua Lu, PhD, Doctor, Department of Orthopaedics, Shanghai Changzheng Hospital, Naval Medical University, No. 415 Fengyang Road, Shanghai 200003, China. xuhualu415@163.com
Research Domain of This Article
Orthopedics
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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World J Clin Cases. Aug 16, 2024; 12(23): 5329-5337 Published online Aug 16, 2024. doi: 10.12998/wjcc.v12.i23.5329
Table 1 Demographics and clinical data of 51 ankylosing spondylitis patients with cervical spine fracture-dislocation
Feature
Male, n = 44
Female, n = 7
Total, n = 51
Age (years)
55.14
59.57
55.4
Injury level
C1/2
5 (11.36)
0 (0)
5 (9.80)
C2/3
2 (4.55)
0 (0)
2 (3.92)
C3/4
2 (4.55)
0 (0)
2 (3.92)
C4/5
5 (11.36)
1 (14.28)
6 (11.76)
C5/6
13 (29.54)
3 (42.86)
16 (31.37)
C6/7
17 (38.64)
3 (42.86)
20 (39.23)
ASIA grade
A
2 (4.55)
1 (14.28)
3 (5.88)
B
5 (11.36)
2 (28.58)
7 (13.73)
C
14 (31.82)
3 (42.86)
17 (33.33)
D
23 (52.27)
1 (14.28)
24 (47.06)
Table 2 Hounsfield units from three levels of sagittal plane reconstruction images of two readers
Segment
Reader 1-Housfield units
Reader 2-Housfield units
Right
Middle
Left
Right
Middle
Left
C2
337
296
334
336
297
334
C3
266
228
261
266
229
260
C4
250
215
249
253
215
250
C5
233
198
226
235
198
225
C6
218
181
214
217
182
215
C7
201
173
196
202
174
196
Average
251
215
247
252
216
247
Table 3 Reliability and agreement of Hounsfield units
Segment
Readers 1-Housfield units
Readers 2-Housfield units
ICC
C2
322.83
322.10
0.96
C3
252.23
251.55
0.94
C4
238.95
239.57
0.96
C5
219.60
218.47
0.91
C6
204.49
205.02
0.99
C7
190.20
190.41
0.98
Average
238.05
237.85
0.93
Table 4 Hounsfield unit thresholds for osteopenia and osteoporosis
Bone mineral Density
T-value
HU
Normal
-1 or greater
≤ 274.33
Osteopenia
-1 to -2.5
228.08-274.33
Osteoporosis
-2.5 or less
≤ 228.08
Citation: Gao ZY, Peng WL, Li Y, Lu XH. Hounsfield units in assessing bone mineral density in ankylosing spondylitis patients with cervical fracture-dislocation. World J Clin Cases 2024; 12(23): 5329-5337