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©The Author(s) 2024.
World J Clin Cases. Aug 6, 2024; 12(22): 5067-5082
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5067
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5067
Table 1 Characteristics of included studies
| Ref. | Average age in yr | Sample size | Interventions | Course | Outcomes | |||
| T | C | T | C | T | C | |||
| Wei and Mao[39], 2021 | 44.44 ± 6.78 | 44.36 ± 6.77 | 51 (34/17) | 51 (32/19) | A (bid) | F | 3 mo | (3) |
| Yu et al[37], 2022 | 43.6 ± 11.8 | 24.8 ± 8.6 | 30 (14/16) | 30 (17/13) | A (bid) | F | 8 wk | (1) (2) (6) |
| Chen and Lin[40], 2021 | 44.97 ± 8.31 | 42.24 ± 7.85 | 60 (30/30) | 60 (32/28) | A (bid) | F | 3 mo | (1) (4) (6) |
| Ma et al[46], 2019 | 43.41 ± 8.02 | 41.68 ± 9.46 | 42 (22/20) | 42 (21/21) | A (bid) | F | 3 mo | (1) (4) (6) |
| Han et al[49], 2018 | 43.44 ± 11.04 | 42.71 ± 10.15 | 32 (17/15) | 32 (16/16) | A (bid) | F | 1 mo | (1) (4) (6) |
| Ma et al[44], 2020 | 41.4 ± 10.8 | 42. 5 ± 9.9 | 70 (46/24) | 70 (44/26) | A (bid) | F | 4 wk | (1) (6) |
| Chen and Yao[53], 2016 | 46.47 ± 8.92 | 46.86 ± 9.05 | 43 (18/25) | 42 (19/23) | A (qd) | F | 4 wk | (1) (5) |
| Xu and Ma[47], 2019 | 56.3 ± 6.8 | 56.1 ± 7.5 | 62 (31/31) | 62 (30/32) | A (qd) | F | 1 mo | (1) (2) (6) |
| Xue[50], 2018 | 40.35 ± 6.24 | 40.59 ± 6.17 | 61 (30/31) | 61 (31/30) | A (qd) | F | 1 mo | (1) |
| Jing et al[41], 2021 | 34.12 ± 5.1 7 | 33.62 ± 5.14 | 52 (28/24) | 50 (27/23) | A (qd) | F | 8 wk | (1) (3) (6) |
| Wei et al[24], 2020 | 43.51 ± 4.52 | 43.45 ± 4.56 | 65 (39/26) | 65 (36/29) | A (qd) | F | 4 wk | (1) (2) (3) (4) |
| Wang et al[48], 2019 | 33.3 ± 3.6 | 33.6 ± 4.0 | 34 (20/14) | 34 (22/12) | A (bid) | F | 4 wk | (1) (6) |
| Liu[42], 2021 | 46.53 ± 10.39 | 46.56 ± 10.41 | 41 (19/22) | 41 (20/21) | A (qd) | F | 4 wk | (1) |
| Liu[54], 2015 | 41.3 ± 2.5 | 42.6 ± 3.7 | 55 (32/23) | 52 (27/25) | A (qd) | F | 4 wk | (1) |
| Nie et al[45], 2020 | 45.27 ± 13.19 | 44.59 ± 12.87 | 60 (29/31) | 60 (25/35) | A (bid) | F | 12 wk | (3) (4) (6) |
| Lu[43], 2021 | 32.8 ± 4.5 | 33.5 ± 4.0 | 30 (16/14) | 30 (18/12) | A (bid) | F | 12 wk | (1) (2) (3) |
| Dai et al[38], 2022 | 39.69 ± 2.45 | 41.35 ± 1.94 | 30 (19/11) | 30 (17/13) | A (bid) | F | 1 wk | (1) |
| Gu[51], 2018 | 45.32 ± 6.13 | 45.11 ± 6.34 | 35 (15/20) | 35 (16/19) | A (qd) | F | 4 wk | (1) (5) |
| Jin and Li[52], 2018 | 48.32 ± 4.52 | 47.88 ± 4.32 | 40 (23/17) | 40 (22/18) | A (bid) | F | 4 wk | (1) |
| Wang et al[88], 2017 | 34.56 ± 5.58 | 34.18 ± 5.25 | 32 (17/15) | 32 (16/16) | B (bid) | F | 4 wk | (1) (6) |
| Yao et al[89], 2021 | 44.1 ± 7.3 | 45.6 ± 8.0 | 65 (29/36) | 62 (30/32) | B (bid) | F | 4 wk | (1) (4) |
| Zhu et al[86],2021 | 43.05 ± 14.53 | 45.12 ± 13.38 | 35 (16/19) | 35 (18/17) | B (bid) | F | 3 mo | (1) (2) (6) |
| Li et al[90], 2021 | 38.16 ± 5.43 | 37.36 ± 6.72 | 25 (14/11) | 25 (16/9) | B (bid) | F | 1 mo | (1) (2) (3) |
| Lei et al[84], 2016 | 45.1 ± 4.9 | 45.1 ± 4.9 | 35 (15/20) | 35 (18/17) | B (bid) | F | 8 wk | (1) (5) (6) |
| Wang and Zhou[82], 2017 | 32.91 ± 4.45 | 33.14 ± 4.78 | 49 (26/23) | 49 (27/22) | B (bid) | F | 6 wk | (1) (3) (6) |
| Chen et al[91], 2018 | 38.5 | 37.9 | 36 (20/16) | 36 (21/15) | B (qd) | F | 3 wk | (1) (3) |
| Sheng et al[83], 2017 | 34.64 ± 2.98 | 37.26 ± 2.47 | 48 (26/22) | 48 (23/25) | B (tid) | F | 4 wk | (1) (6) |
| Ding[87], 2019 | 34.1 ± 3.8 | 34.5 ± 3.7 | 38 (20/18) | 38 (22/16) | B (bid) | F | 8 wk | (1) (2) (6) |
| Chen and Ye[85], 2014 | 32.15 ± 4.82 | 32.84 ± 4.36 | 39 (21/18) | 39 (20/19) | B (bid) | F | 6 wk | (1) (3) (6) |
| Wang[34], 2016 | 25.6 ± 2.3 | 26.5 ± 4.1 | 58 (32/26) | 58 (35/23) | C (qd) | F | 3 wk | (1) (5) (6) |
| Meng[33], 2017 | 54 ± 18 | 51 ± 17 | 28 (18/10) | 28 (16/12) | C (qd) | F | 3 wk | (1) (2) (6) |
| Zhu and Xie[30], 2009 | 28 | 27 | C (qd) | F | 4 wk | (1) (5) (6) | ||
| Liu[35], 2015 | 38.9 ± 3.4 | 37.4 ± 2.5 | 30 (14/16) | 26 (11/15) | C (qd) | F | 8 wk | (1) |
| Cai et al[32], 2022 | 30.24 ± 2.17 | 30.17 ± 2.0 | 38 (17/21) | 38 (19/19) | C (qd) | F | 8 wk | (1) (3) (6) |
| Ma et al[36], 2016 | 41.2 | 39.8 | 26 (14/12) | 20 (11/9) | C (qd) | F | 3 mo | (1) (5) |
| Cheng et al[29], 2011 | 65.3 ± 2.6 | 65.3 ± 2.6 | 22 | 22 | C (qd) | F | 4 wk | (1) (6) |
| Xu and Wang[31], 2010 | 38.4 | 38.4 | 42 (29/13) | 42 (25/17) | C (qd) | F | 4 wk | (1) (6) |
| Wang[55], 2021 | 31.5 ± 7.1 | 31.9 ± 5.4 | 48 (26/22) | 48 (27/21) | D (tid) | F | 3 mo | (1) |
| Li and Wang[57], 2021 | 47.33 ± 8.52 | 46.50 ± 7.87 | 45 (26/19) | 45 (25/20) | D (bid) | F | 8 wk | (1) (3) |
| Yin et al[56], 2021 | 43.6 ± 5.2 | 42.3 ± 5.6 | 60 (31/29) | 60 (30/30) | D (qd) | F | 8 wk | (1) (2) (3) (5) (6) |
| Liu et al[58], 2021 | 39.79 ± 10.41 | 40.28 ± 9.85 | 58 (36/22) | 58 (34/24) | D (tid) | F | 3 mo | (1) (6) |
| Zhu et al[59], 2020 | 38.5 ± 7.4 | 40.2 ± 7.8 | 25 (15/10) | 25 (16/9) | D (tid) | F | 3 mo | (3) |
| Liang and Wang[60], 2020 | 43.02 ± 11.36 | 44.32 ± 10.63 | 61 (44/17) | 61 (42/19) | D (bid) | F | 8 wk | (1) (3) (6) |
| Tian et al[61], 2019 | 42.82 ± 10.26 | 42.74 ± 10.1 | 66 (35/31) | 66 (34/32) | D (tid) | F | 12 wk | (1) (3) (5) |
| Zhang[62], 2018 | 51.31 ± 14.71 | 50.00 ± 15.14 | 16 (8/8) | 14 (6/8) | D (tid) | F | 12 wk | (1) (5) |
| Yang and Yan[63], 2018 | 38.25 ± 7.36 | 37.85 ± 7.06 | 43 (26/17) | 43 (25/18) | D (tid) | F | 12 wk | (1) (3) (6) |
| Zhou et al[65], 2018 | 41.68 ± 8.05 | 42.17 ± 9.12 | 50 (29/21) | 50 (27/23) | D (tid) | F | 8 wk | (1) (6) |
| Zhou and Hu[66], 2017 | 50.7 ± 14.664 | 40.87 ± 14.439 | 30 (14/16) | 30 (15/15) | D (tid) | F | 24 wk | (1) (5) (6) |
| Wang[67], 2016 | 38.87 ± 10.15 | 38.62 ± 9.97 | 40 (24/16) | 40 (22/18) | D (tid) | F | 8 wk | (1) |
| Zou[68], 2015 | 41.8 ± 2.1 | 42.1 ± 1.8 | 49 (31/18) | 48 (30/18) | D (tid) | F | 8 wk | (1) |
| Li[69], 2015 | 39.5 ± 8.2 | 40.8 ± 7.6 | 36 (21/15) | 37 (23/14) | D (tid) | F | 8 wk | (1) (3) |
| Xu[64], 2015 | 34.25 ± 4.56 | 34.25 ± 4.56 | 40 | 40 | D (tid) | F | 2 mo | (1) (3) |
| Xin et al[70], 2015 | 39.5 ± 8.2 | 40.8 ± 7.6 | 37 (22/15) | 38 (17/21) | D (tid) | F | 8 wk | (1) (3) |
| Xu and Chen[71], 2015 | 40.3 ± 11.5 | 41.1 ± 11.7 | 49 (26/23) | 49 (25/24) | D (qd) | F | 4 wk | (1) (2) (5) (6) |
| Chen et al[72], 2013 | 41.7 ± 8.1 | 38.2 ± 7.6 | 48 (24/24) | 48 (24/24) | D (tid) | F | 2 mo | (1) |
| Wei et al[73], 2013 | 18-58 | 19-60 | 23 (16/7) | 23 (14/9) | D (tid) | F | 12 wk | (1) (3) |
| Chen[74], 2013 | 42.6 ± 7.2 | 41.4 ± 8.3 | 40 (28/12) | 40 (30/10) | D (tid) | F | 12 wk | (1) |
| Lu[78], 2021 | 48.89 ± 2.67 | 48.21 ± 2.12 | 35 (25/10) | 35 (25/10) | E (tid) | F | 8 wk | (1) (3) |
| Shen[76], 2020 | 40.38 ± 3.26 | 40.25 ± 3.79 | 42 (24/18) | 42 (22/20) | E (bid) | F | 1 mo | (1) |
| Luo[77], 2019 | 40.3 ± 2.0 | 40.3 ± 2.0 | 42 | 42 | E (tid) | F | 1 mo | (1) (6) |
| Chen[81], 2019 | 49.2 ± 5.1 | 49.3 ± 5.1 | 50 (31/19) | 50 (30/20) | E (bid) | F | 8 wk | (1) |
| Yao[80], 2018 | 42.3 ± 13.6 | 41.7 ± 12.8 | 36 (16/20) | 36 (15/21) | E (bid) | F | 4 wk | (1) (6) |
| Zhao et al[79], 2017 | 43.22 ± 5.92 | 46.14 ± 6.28 | 30 (14/16) | 30 (15/15) | E (tid) | F | 8 wk | (1) (6) |
| Liu[75], 2014 | 39.9 ± 7.4 | 39.7 ± 7.3 | 45 (21/24) | 44 (19/25) | E (bid) | F | 1 mo | (1) (6) |
Table 2 Ranking list of different interventions
| Interventions | Effective | Baron | IBDQ | TNF | Recurrence rate |
| BTWT | 0.03 | 0.31 | 0.73 | 0.01 | 0.70 |
| CYN | 0.52 | - | - | 0.01 | - |
| SLBZS | 0.00 | 0.09 | - | 0.03 | 0.24 |
| SYT | 0.03 | 0.17 | 0.26 | 0.70 | - |
| XLS | 0.41 | 0.43 | - | 0.26 | 0.05 |
| Mesalazine | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
- Citation: Zhao ZH, Dong YH, Jiang XQ, Wang J, Qin WL, Liu ZY, Zhang XQ, Wei YJ. Five commonly used traditional Chinese medicine formulas in the treatment of ulcerative colitis: A network meta-analysis. World J Clin Cases 2024; 12(22): 5067-5082
- URL: https://www.wjgnet.com/2307-8960/full/v12/i22/5067.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v12.i22.5067