Central nervous injury risk factors after endovascular repair of a thoracic aortic aneurysm with type B aortic dissection

Table 1 Clinical characteristics of two groups of patients

Variable	Non-injury group (n = 147)	Injury group (n = 159)	χ2/t	P value
Age	50.74 ± 7.51	59.68 ± 4.15	13.014	< 0.001
History of drinking			0.753	0.385
Yes	75	89
No	72	70
History of smoking			0.005	0.944
Yes	78	85
No	69	74
History of diabetes			1.397	0.237
Yes	27	38
No	120	121
History of surgery			0.007	0.931
Yes	29	32
No	118	127
History of hypertension			29.913	< 0.001
Yes	87	138
No	60	21
Coronary heart disease			0.027	0.871
Yes	26	27
No	121	132
Cerebral infarction			0.268	0.605
Yes	4	6
No	143	153
COPD			1.029	0.310
Yes	35	46
No	112	113
Hyperlipidemia			1.723	0.189
Yes	11	19
No	136	140
Staging			0.281	0.596
Acute stage	39	38
Chronic stage	108	121
Low back pain			0.108	0.742
Yes	101	112
No	46	47
Left ventricular ejection fraction	61.44 ± 8.11	59.67 ± 9.23	1.768	0.078
Aortic dissection location			1.285	0.733
Descending aortic isthmus	109	117
Middle thoracic aorta	27	25
Diaphragm level	9	13
Visceral artery	2	4

COPD: Chronic obstructive pulmonary disease.

Table 2 Surgical-related characteristics of the two groups of patients

Variable	Non-injury group (n = 147)	Injury group (n = 159)	χ2/t	P value
Type of main stent			0.166	0.983
Captivia	100	108
Zenith	17	19
Ankura	28	29
Grink	2	3
Vertebral stent	45	48	0.007	0.936
Length of stent	189.91 ± 23.11	186.87 ± 23.37	1.143	0.254
Coverage of left subclavian artery			0.299	0.585
Partial coverage	85	87
Complete coverage	62	72
Maximum diameter of descending aorta	4.21 ± 0.34	4.23 ± 0.27	0.564	0.573
Surgery time	88.93 ± 8.29	109.31 ± 7.56	22.496	< 0.001
Mechanical ventilation time	101.36 ± 10.23	119.52 ± 9.28	16.283	< 0.001
Success rate of surgery	147	159	-	-

Table 3 Postoperative-related characteristics of the two groups of patients

Variable	Noninjury group (n = 147)	Injury group (n = 159)	t value	P value
ICU stay time (day)	3.58 ± 0.56	6.70 ± 1.37	25.723	< 0.001
Hospitalization time (day)	17.98 ± 7.65	19.27 ± 6.42	1.602	0.109
Urine volume on the first day after surgery (mL)	1427 ± 621.32	1409 ± 601.26	0.258	0.797
Postoperative recovery time (hour)	1.68 ± 0.56	3.17 ± 1.37	12.303	< 0.001
Blood pH value on the first day after surgery	7.44 ± 0.16	7.37 ± 0.17	3.714	< 0.001
PaO2 on the first day after surgery	101.71 ± 35.87	81.63 ± 37.17	4.801	< 0.001

ICU: Intensive care unit.

Table 4 Multivariate logistic regression analysis of postoperative central nervous system injury in patients

Variable	β	SE	Wald	P	OR	95%CI
Age (year)	0.387	0.172	5.063	0.024	1.473	1.051–2.063
Surgery time (hour)	0.629	0.186	11.436	0.001	1.875	1.303–2.701
History of hypertension	1.053	0.221	22.702	< 0.001	2.866	1.859–4.420
Mechanical ventilation time (hour)	0.445	0.219	4.129	0.042	1.561	1.016–2.397
ICU stay time (day)	0.699	0.187	13.972	< 0.001	2.012	1.394–2.902

ICU: Intensive care unit.