Effect of sodium hyaluronate combined with rehabilitation training on knee joint injury caused by golf

Table 1 The final criteria for diagnosing suspicious lesions

No.	Criteria for diagnosing suspicious lesions
1	The results of two or more imaging techniques were consistent
2	The diagnosis was confirmed by pathological examination after operation or puncture
3	SPECT/CT follow-up review was combined with clinical history and other laboratory tests

SPECT/CT: Single-photon emission computed tomography/computed tomography.

Table 2 Operations procedures of enzyme-linked immunosorbent assay

No.	Operations procedures of ELISA
1	Coating: the antigen or antibody solution to be detected was coated on the microporous plate and adsorbed on the pore wall
2	Blocking: a certain concentration of protein (such as bovine serum albumin) was added to block unadsorbed pore walls to avoid non-specific binding
3	Addition of a certain concentration of detection antibody: the detection antibody labeled with enzyme was added to the well, and the antigen or antibody has been adsorbed
4	Wash: the unbound antibody in the hole was absorbed with a buffer solution
5	Addition of substrate: substrate was added to catalyze the reaction by the enzyme to produce a measurable signal
6	Reading plate: the signal is read by the enzyme marker to calculate the concentration of antigen or antibody

ELISA: Enzyme-linked immunosorbent assay.

Table 3 Comparison of knee joint function (mean ± SD)

Group	n	IKDC score		Lysholm score
		Before	After	Before	After
A	40	48.74 ± 5.85	87.24 ± 7.29a	47.11 ± 4.85	92.28 ± 6.29a
B	40	46.53 ± 5.64	70.42 ± 6.45a	46.62 ± 5.33	72.37 ± 5.57a
t		1.720	10.929	0.430	14.988
P value		0.089	0.000	0.668	0.000

^aP < 0.001. IKDC: International Knee Documentation Committee.

Table 4 VAS and SF-36 scores

Group	n	VAS score		SF-36 score
		Before	After	Before	After
A	40	6.53 ± 1.64	1.24 ± 0.29a	41.46 ± 10.50	68.28 ± 15.29b
B	40	6.94 ± 1.05	2.26 ± 0.56a	41.82 ± 10.44	58.48 ± 15.97b
t		-1.332	-10.230	-0.154	2.803
P value		0.187	0.000	0.878	0.006

^aP < 0.001;

^bP < 0.01.

Table 5 The levels of inflammatory factors

Group	n	IL-1β (pg/mL)		IL-8 (ng/L)		TNF-α (μg/L)
		Before	After	Before	After	Before	After
A	40	42.56 ± 8.23	23.42 ± 4.37a	58.34 ± 8.84	37.62 ± 6.38a	22.41 ± 3.58	11.38 ± 3.14a
B	40	43.21 ± 7.25	30.37 ± 5.42a	60.14 ± 10.52	48.26 ± 8.44a	21.82 ± 4.10	15.42 ± 2.85a
t		-0.345	-6.313	-0.829	-6.360	0.686	-6.026
P value		0.709	0.000	0.410	0.000	0.495	0.000

^aP < 0.001. IL: Interleukin; TNF-α: tumor necrosis factor alpha.