Retrospective Study
Copyright ©The Author(s) 2024.
World J Clin Cases. Jul 16, 2024; 12(20): 4166-4173
Published online Jul 16, 2024. doi: 10.12998/wjcc.v12.i20.4166
Table 1 General patient information, mean ± SD
Group
Experimental group
Control group
F/t
P value
Age (yr)54.73 ± 5.3165.5 ± 3.15-0.7220.473
Gender (Male/female)13/1714/ 160.5910.444
Body mass index24.27 ± 1.8123.85 ± 2.130.8080.421
Smoking history (pack/yr)16/1415/ 140.6440.425
High blood pressure (Yes/No)14/1613/170.5860.446
Diabetes (Yes/No)8/227/230.5860.446
Glycosylated hemoglobin (%)5.37 ± 0.685.62 ± 0.72-1.0900.280
Total cholesterol (mmoL/L)6.39 ± 0.686.40 ± 0.72-0.0690.944
Triglyceride (mmoL/L)1.43 ± 0.491.58 ± 0.42-1.2840.203
Low density lipoprotein (mmoL/L)3.06 ± 0.553.27 ± 0.45-1.6000.114
Phospholipid protein A1 (g/L)0.95 ± 0.210.87 ± 0.171.5920.116
Phospholipid protein B (g/L)1.46 ± 0.351.42 ± 0.360.4310.667
Lipoprotein (mg/dL)127.14 ± 7.93134.31 ± 9.39-1.9270.058
Table 2 Comparison of respiratory mechanics indicators before treatment, mean ± SD
Group
Time
Cst (mL/cm H2O)
Raw (cm H2O/L/s)
mPaw (cm H2O)
Pplat (cm H2O)
PIP (cm H2O)
Test groupBefore treatment44.39 ± 3.8715.63 ± 2.1818.21 ± 3.1724.33 ± 3.6926.20 ± 4.87
After treatment51.97 ± 4.8412.26 ± 1.6415.90 ± 2.3721.44 ± 3.0124.06 ± 3.12
Control groupBefore treatment44.00 ± 3.5815.86 ± 1.8018.80 ± 2.7124.51 ± 2.7126.33 ± 4.15
After treatment49.49 ± 4.4714.80 ± 1.9918.72 ± 2.0324.50 ± 3.1227.81 ± 4.03
t/P (before and after treatment)0.404/0.688-0.449/0.655-0.774/0.442-0.215/0.83-0.111/0.912
t/P (before and after treatment)2.06/0.044-0.541/< 0.01-4.954/< 0.01-3.871/< 0.01-4.027/< 0.01
Table 3 Comparison of blood gas analysis indicators before treatment, mean ± SD
Group
Time
SpO2 (%)
PaO2 (mmHg)
OI
Test groupBefore treatment93.15 ± 1.7980.24 ± 7.1518.58 ± 2.50
After treatment94.68 ± 1.6892.53 ± 8.1315.28 ± 1.99
Control groupBefore treatment93.34 ± 2.1678.78 ± 7.2819.35 ± 2.57
After treatment93.52 ± 2.3286.65 ± 6.1518.16 ± 1.75
t/P (before and after treatment)-0.37/0.7130.786/0.435-1.19/0.239
t/P (before and after treatment)2.231/0.033.159/< 0.01-5.952/< 0.01
Table 4 Comparison of serum inflammatory factor levels before treatment, mean ± SD
Group
Time
CRP (mg/L)
PCT (ng/mL)
Test groupBefore treatment41.98 ± 4.452.43 ± 0.81
After treatment40.29 ± 3.382.46 ± 0.64
Control groupBefore treatment41.83 ± 2.071.16 ± 0.5
After treatment29.53 ± 5.032.40 ± 0.48
t/P (before and after treatment)0.163/0.8710.451/0.654
t/P (before and after treatment)9.732/< 0.017.259/< 0.01
Table 5 Changes in serum cortisol and high mobility group protein B1 levels, mean ± SD
Group
Time
COR (μg/dL)
HMGB1 (ng/mL)
Test groupBefore treatment19.33 ± 2.3032.20 ± 3.27
After treatment14.94 ± 2.1928.30 ± 2.58
Control groupBefore treatment18.65 ± 2.3633.70 ± 2.98
After treatment18.25 ± 2.2533.17 ± 3.05
t/P (before and after treatment)1.125/0.265-1.742/0.087
t/P (before and after treatment)-5.77/< 0.01-6.684/< 0.01