Identification of risk factors and construction of a nomogram predictive model for post-stroke infection in patients with acute ischemic stroke

Table 1 Comparison of two sets of baseline data, n (%)

	Non-infection (n = 158)	Infection (n = 48)	z/t/χ2	P value
Gender			0.015	0.903
Male	97 (61.4)	29 (60.4)
Female	61 (38.6)	19 (39.6)
Age (years)	60.16 ± 7.86	67.81 ± 7.88	-5.902	0.000
Hypertension			2.423	0.120
No	56 (35.4)	23 (47.9)
Yes	102 (64.6)	25 (52.1)
Hyperlipidemia			0.043	0.836
No	133 (84.2)	41 (85.4)
Yes	25 (15.8)	7 (14.6)
Coronary heart disease			0.020	0.887
No	137 (86.7)	42 (87.5)
Yes	21 (13.3)	6 (12.5)
Atrial fibrillation			0.000	1.000
No	145 (91.8)	44 (91.7)
Yes	13 (8.2)	4 (8.3)
Smoking			0.087	0.768
No	95 (60.1)	30 (62.5)
Yes	63 (39.9)	18 (37.5)
Drinking			0.121	0.728
No	57 (36.1)	16 (33.3)
Yes	101 (63.9)	32 (66.7)
Diabetes			24.42	0.000
No	127 (80.4)	21 (43.8)
Yes	31 (19.6)	27 (56.3)
Disturbance of consciousness			25.115	0.000
No	140 (88.6)	27 (56.3)
Yes	18 (11.4)	21 (43.8)
NIHSS score at admission [M (IQR), score]	9 (8.11)	10 (9.13)	-2.668	0.008
Invasive operation			11.115	0.001
No	119 (75.3)	24 (50.0)
Yes	39 (24.7)	24 (50.0)
COPD			16.544	0.000
No	116 (73.4)	20 (41.7)
Yes	42 (26.6)	28 (58.3)

COPD: Chronic obstructive pulmonary disease; NIHSS: National Institutes of Health Stroke Scale; IQR: Interquartile range.

Table 2 Assignment table

Variable	Index	Assigned method
X1	Age	Continuous variable
X2	Diabetes	No = 0; Yes = 1
X3	Disturbance of consciousness	No = 0; Yes = 1
X4	NIHSS score at admission	Continuous variable
X5	Invasive operation	No = 0; Yes = 1
X6	COPD	No = 0; Yes = 1

COPD: Chronic obstructive pulmonary disease; NIHSS: National Institutes of Health Stroke Scale; IQR: Interquartile range.

Table 3 Logistic analysis of risk factors for post-stroke infection in patients with acute ischemic stroke

	B	SE	Wald	P value	OR	95%CI
Age	0.105	0.029	13.364	0.000	1.111	1.050-1.175
Diabetes	1.026	0.447	5.277	0.022	2.791	1.163-6.701
Disturbance of consciousness	1.350	0.510	7.011	0.008	3.856	1.420-10.471
NIHSS score at admission	0.335	0.106	10.023	0.002	1.398	1.136-1.719
Invasive operation	1.139	0.452	6.362	0.012	3.123	1.289-7.567
COPD	1.215	0.430	7.979	0.005	3.372	1.451-7.836

COPD: Chronic obstructive pulmonary disease; NIHSS: National Institutes of Health Stroke Scale; IQR: Interquartile range.