Diagnostic efficacy of virtual organ computer-assisted analysis in measuring the volume ratio of subchorionic hematoma with serum progesterone

Table 1 Comparison of the demographic data between the two groups, n (%)

	Adverse pregnancy group (n = 57)	Normal pregnancy group (n = 96)	P value
Age	29.4 (4.2)	28.9 (3.5)	0.424
Parity			0.390
Primipara	31 (53.8)	58 (60.4)
Multipara	26 (46.2)	38 (39.6)
Vaginal bleeding			0.028
Yes	24 (42.1)	17 (17.7)
No	33 (57.9)	79 (82.3)
Abdominal pain			0.891
Yes	33 (57.9)	58 (60.4)
No	24 (42.1)	38 (39.6)
Hysteromyoma			1.000
Yes	3 (5.3)	4 (4.2)
No	54 (94.7)	92 (95.8)
Diabetes before pregnancy			0.713
Yes	2 (3.5)	4 (4.2)
No	55 (96.5)	92 (95.8)
Chronic hypertension			1.000
Yes	2 (3.5)	3 (3.1)
No	55 (96.5)	93 (96.9)

Table 2 Comparison of ultrasound parameters between patients in the adverse and normal pregnancy groups

	Adverse pregnancy group (n = 57)	Normal pregnancy group (n = 96)	P value
SCH
Cs (cm)	4.6 (3.1, 6)	3.2 (2.1, 4.2)	< 0.001
Ss (cm2)	2.1 (1.5, 3)	1.3 (0.8, 1.9)	< 0.001
3DVs (cm3)	2.9 (2.2, 3.5)	1.5 (0.6, 2.4)	< 0.001
GS
Cg (cm)	9 (7.2, 10.5)	9.2 (7.9, 11.6)	0.214
Sg (cm2)	6.6 (3.6, 9.9)	7.1 (4.4, 10.7)	0.411
3DVg (cm3)	8.4 (5.3, 15.6)	12.6 (6.4, 21.3)	0.057
SCH/GS
Cs/Cg	0.5 (0.4, 0.6)	0.3 (0.2, 0.4)	< 0.001
Ss/Sg	0.3 (0.2, 0.5)	0.2 (0.1, 0.3)	< 0.001
3DVs/3DVg	0.3 (0.2, 0.5)	0.1 (0.1, 0.2)	< 0.001

SCH: Subchorionic hematoma; Cs: The circumference of SCH, Ss: The surface area of SCH; Cg: The circumference of GS; Sg: The surface area of GS; 3DVs: The three-dimensional volume of SCH; 3DVg: The three-dimensional volume of GS.

Table 3 Differential diagnostic efficacy of different subchorionic hematoma sizes for adverse versus normal pregnancy

	ROC	Cut-off	Sensibility	Specificity	Positive predictive value	Negative predictive value
Cs (cm)	0.671 (0.579, 0.763)	4.340	0.561	0.760	0.582	0.745
Ss (cm2)	0.697 (0.611, 0.784)	1.350	0.825	0.510	0.500	0.830
3DVs (cm3)	0.743 (0.661, 0.826)	2.180	0.807	0.719	0.630	0.863
Cs/Cg	0.262 (0.180, 0.344)	0.400	0.737	0.677	0.575	0.713
Ss/Sg	0.710 (0.624, 0.797)	0.360	0.474	0.885	0.711	0.739
3DVs/3DVg	0.767 (0.691, 0.844)	0.220	0.702	0.750	0.625	0.809

SCH: Subchorionic hematoma; Cs: The circumference of SCH; Ss: The surface area of SCH; Cg: The circumference of GS; Sg: The surface area of GS; 3DVs: The three-dimensional volume of SCH (3DVs); 3DVg: Three-dimensional volume of GS; ROC: Receiver operating characteristic.

Table 4 3DVs/3DVg and progesterone for early adverse pregnancy

	ROC	Cut-off	Sensibility	Specificity	Positive predictive value	Negative predictive value
3DVs/3DVg	0.767 (0.691, 0.844)	0.220	0.702	0.750	0.625	0.809
Progesterone	0.649 (0.557, 0.741)	18.2	0.677	0.625	0.756	0.530
3DVs/3DVg combined progesterone	0.824 (0.756, 0.891)	0.664	0.770	0.821	0.881	0.676

3DVs: Three-dimensional volume of subchorionic hematoma; 3DVg: Three-dimensional volume of GS; ROC: Receiver operating characteristic.