Li M, Su P, Zhou LM. Live births from in vitro fertilization-embryo transfer following the administration of gonadotropin-releasing hormone agonist without gonadotropins: Two case reports. World J Clin Cases 2023; 11(9): 2067-2073 [PMID: 36998947 DOI: 10.12998/wjcc.v11.i9.2067]
Corresponding Author of This Article
Li-Ming Zhou, BMed, Chief Physician, Reproductive Center, Ningbo Women and Children’s Hospital, No. 339 Liuting Street, Ningbo 315000, Zhejiang Province, China. zhou.li.ming@163.com
Research Domain of This Article
Reproductive Biology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 26, 2023; 11(9): 2067-2073 Published online Mar 26, 2023. doi: 10.12998/wjcc.v11.i9.2067
Table 1 Protocol timeline for Case 1
Date
Protocol
June 9, 2015
Triptorelin acetate 0.1 mg/d for 14 d
June 23, 2015
HCG 5000 IU im
June 25, 2015
Oocyte retrieval
June 28, 2015
D3 embryos frozen
June 30, 2015
D5 embryos frozen
August 31, 2015
Two blastospheres were transferred
Table 2 Hormone concentrations before and after treatment for Case 1
Hormone concentrations before treatment
Hormone concentrations after treatment
FSH in mIU/mL
8.17
8.68
LH in mIU/mL
5.15
5.17
E2 in pg/mL
90.00
5110.00
Progesterone in ng/mL
0.67
4.47
Table 3 Protocol timeline for Case 2
Date
Protocol
March 28, 2015
Triptorelin acetate 0.1 mg/d for 14 d
March 12, 2015
HCG 10000 IU im
March 14, 2015
Oocyte retrieval
March 17, 2015
D3 embryos frozen
June 14, 2015
Two D3 embryos were transferred
Table 4 Hormone concentrations before and after treatment for Case 2
Hormone concentrations before treatment
Hormone concentrations after treatment
FSH in mIU/mL
6.72
2.29
LH in mIU/mL
4.04
1.38
E2 in pg/mL
33.00
2664.00
Progesterone in ng/mL
0.62
3.36
Citation: Li M, Su P, Zhou LM. Live births from in vitro fertilization-embryo transfer following the administration of gonadotropin-releasing hormone agonist without gonadotropins: Two case reports. World J Clin Cases 2023; 11(9): 2067-2073