Pinheiro FD, Lopes LW, Dórea RSDM, Araújo GRL, Silva FAFD, de Brito BB, Cordeiro Santos ML, Júnior GMS, de Lorenzo Barcia MTA, Marques RA, Botelho AB, Dantas ACS, Costa DT, Teixeira AF, Souza CL, Marques LM, Campos GB, Oliveira MV, de Magalhães Queiroz DM, Freire de Melo F. Epidemiological and clinical characteristics of COVID-19 in a Brazilian public hospital. World J Clin Cases 2023; 11(8): 1761-1770 [PMID: 36970001 DOI: 10.12998/wjcc.v11.i8.1761]
Corresponding Author of This Article
Fabrício Freire de Melo, MSc, PhD, Postdoc, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormínio Barros, 58, Candeias, Vitória da Conquista 45029-094, Bahia, Brazil. freiremelo@yahoo.com.br
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 16, 2023; 11(8): 1761-1770 Published online Mar 16, 2023. doi: 10.12998/wjcc.v11.i8.1761
Table 1 Prevalence of outcomes/destinations in the studied population, n = 101
Prevalence of outcomes/destinations
n (%)
Discharge or transfer from the ICU
48 (47.5)
Death
47 (46.5)
Transfer
6 (5.9)
Table 2 Hematologic risk factors associated with death in the patients
Hematologic values
With death, mean ± SD
Without death, mean ± SD
P value
Hemoglobin, mg/dL
11.31 ± 2.96
11.70 ± 2.79
0.55
Leukocytes, mm³
14.45 ± 6.88
14.29 ± 8.71
0.92
CRP, g/L
143.46 ± 150.76
147.53 ± 201.60
0.77
Platelets, g/L
141.49 ± 9.55
154.88 ± 72.91
< 0.001
Table 3 Age, sex, comorbidities, and laboratory tests associated with the main outcomes, n (%)
Comorbidities
Death, n
Discharged, n
P value
Death, mean ± SD
Discharged median ± SD
Hypertension
33 (53.2)
29 (46.8)
0.15
Diabetes
18 (58.1)
13 (41.9)
0.14
Cardiovascular disease
11 (50.0)
11 (50.0)
0.54
Obesity
6 (50.0)
6 (50.0)
0.58
Chronic kidney disease
8 (66.7)
4 (33.3)
0.15
Chronic obstructive pulmonary disease
2 (50.0)
2 (50.0)
0.67
Autoimmune diseases
0 (0)
1 (100)
0.51
At least 2 comorbidities
28 (60.9)
18 (39.1)
0.01
Laboratory tests
Hemoglobin, mg/dL
0.55
11.31 ± 2.96
11.70 ± 2.79
Leukogram, mm³
0.93
14.448 ± 6.878
14.292 ± 8.705
CRP, g/L
0.18
143.46 ± 150.76
147.53 ± 201.60
Platelets, g/L
< 0.001
141.49 ± 9.55
154.88 ± 72.91
Serum sodium, mEq/L
0.35
143.00 ± 9.79
140.62 ± 10.70
AST, U/L
0.22
54.20 ± 32.41
92.83 ± 24.10
ALT, U/L
0.7
26.00 ± 13.78
81.90 ± 90.50
Lactic dehydrogenase, U/L
486.00 ± 48.08
274
0.17
Table 4 Relationship between symptoms and the main clinical outcomes, n (%)
Symptom
Death
Discharged
P value
Dyspnea
36 (46.8)
41 (53.2)
0.09
Cough
23 (40.4)
34 (59.6)
0.01
Fever
14 (41.2)
20 (58.8)
0.15
Myalgia
9 (42.9)
12 (57.1)
0.30
Diarrhea
6 (66.6)
3 (33.3)
0.24
Headache
4 (44.0)
5 (55.0)
0.02
Nausea
7 (87.5)
1 (12.5)
0.02
Vomiting
6 (85.7)
1 (14.3)
0.05
Chills
1 (20.0)
4 (80.0)
0.18
Taste changes
1 (50.0)
1 (50.0)
0.75
Anosmia
1 (50.0)
1 (50.0)
0.75
Citation: Pinheiro FD, Lopes LW, Dórea RSDM, Araújo GRL, Silva FAFD, de Brito BB, Cordeiro Santos ML, Júnior GMS, de Lorenzo Barcia MTA, Marques RA, Botelho AB, Dantas ACS, Costa DT, Teixeira AF, Souza CL, Marques LM, Campos GB, Oliveira MV, de Magalhães Queiroz DM, Freire de Melo F. Epidemiological and clinical characteristics of COVID-19 in a Brazilian public hospital. World J Clin Cases 2023; 11(8): 1761-1770