Development of Henoch-Schoenlein purpura in a child with idiopathic hypereosinophilia syndrome with multiple thrombotic onset: A case report

Table 1 Before and after are different patients

No.	Ref.	Number of cases	Symptom	Thrombotic events	Treat	Prognosis
1	[6]	2	Papules/multiple painful, papules and; plaques over both legs	DVT of the lower extremities, PE, left renal vein thrombosis/dermal microthrombi	Prednisolone and anticoagulants/unknown	Died/unknown
2	[7]	1	Pain and swelling of both legs accompanied with fever	DVT of the lower extremities, PE, portal thrombosis, mesenteric venous thrombosis	Prednisone, coumadin	Improved
3	[8]	2	Progressive chest pain, cough, hemoptysis, painless right leg swelling and 10 d history of intermittent diarrhea/pain and swelling of right leg, hemoptysis	DVT of the right lower extremity, PE	Anticoagulant, corticosteroids	Improved
4	[9]	1	Shortness of breath, chest pain, digital ischaemia	DVT of the lower extremities, PE, portal vein; thrombus, vena cava thrombus	Inferior vena cava filter insertion, thrombolysis, prednisolone, anticoagulation	Improved
5	[10]	1	Distal lower extremity paresthesias and fatigue	Cerebral arteriolar thromboembolism	Methylprednisolone	Died
6	[11]	1	Headaches, vomiting, a rise in blood pressure	Sagittal sinus vein thrombosis	Anticoagulation	Died
7	[12]	1	Fever, respiratory distress	Right atrial and ventricular thrombosis	Anticoagulation	Improved
8	[13]	2	Pain in the left inguinal region/palsy and pain in the right middle finger	Thrombus formation from the trunk of the portalvein, superior mesenteric vein, splenic vein, and right hepatic vein to deep veins in the lower extremities/A thrombus of the muscular artery in the subcutaneous region	Splenectomy, prednisolone, anticoagulation/prednisolone, cyclosporin A, prostaglandin E1, the finger was amputated	Improved
9	[14]	1	Left upper abdominal pain, dry cough, a painful, swollen left leg	DVT of the left lower extremity	Prednisolone, anticoagulation	Improved
10	[15]	1	Headache, vomiting	Superior sagittal sinus thrombosis	Anticoagulation	Improved
11	[16]	1	Fever	Portal vein thrombosis	Corticosteroids, anticoagulation	Improved
12	[17]	1	Disorientation, decreased muscle strength in the upper limbs, nonspecific chest pain	Arch of the aorta thrombus	Corticosteroids, anticoagulation	Aggravation
13	[18]	1	Cough, malaise, loss of appetite, and fever	DVT of the lower extremities, PE, and both right and left biventricular mural thrombi	Glucocorticoids	Improved
14	[19]	1	Swelling in the right parotid gland	Transverse and sigmoid sinuses thrombosis	Methylprednisolone	Died
15	[20]	1	Fever, hemoptysis, and chest pain	DVT of the lower extremities, PE	Dexamethasone, anticoagulation	Improved
16	[21]	3	Unknown	Superficial venous thrombophlebitis of the lower extremities	Prednisone, anticoagulation	Improved

DVT: Deep venous thrombosis; PE: Pulmonary embolism.