Intracranial infection accompanied sweet’s syndrome in a patient with anti-interferon-γ autoantibodies: A case report

Table 1 Changes in carbohydrate antigen 125, immunoglobulins G and inhibitory lymphocytes

	Before therapy (2021/5/9)	After treatment (2021/7/8)
CA125 (≤ 35 U/mL)	46	12.7
IgG (8-16 g/L)	23.85	17.91
Th (19%-48%)	9.3	18.7

After treatment, the values of CA125, IgG, and Th returned to the normal counts. CA125: Carbohydrate antigen 125, IgG: Immunoglobulins G; Th: Inhibitory lymphocytes.

Table 2 Cerebrospinal fluid analysis

CSF parameter	Normal	Before therapy (2021/5/11)	After treatment (2021/5/17)
CSF pressure (mmH2O)	80-180	230	160
Appearance	Clear	Clear	Clear
Pandy test	Negative	Weak positive	Weak positive
CSF WBC (106/L)	0-5	166	15
CSF N (%)		76.1	17.9
CSF L (%)		23.6	72
CSF E (%)		0.3	0.1
CSF protein (g/L)	0.08-0.45	0.56	0.72
CSFchloride ion (mmol/L)	120-130	118	113
CSF glucose (mmol/L)	2.5-4.4	2.66	2.48

Upon admission, the patient showed a high cerebrospinal fluid white blood cell (CSF WBC) count and a high CSF pressure. After treatment, the intracranial infection was controlled, which mainly indicated that the CSF pressure had restored and the CSF WBC count had decreased. CSF: Cerebrospinal fluid; CSF WBC: Cerebrospinal fluid white blood cell; CSF N: Cerebrospinal fluid neutrophils; CSF L: Cerebrospinal fluid lymphocytes; CSF E: Cerebrospinal fluid eosinophilic.