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©The Author(s) 2023.
World J Clin Cases. Nov 16, 2023; 11(32): 7806-7813
Published online Nov 16, 2023. doi: 10.12998/wjcc.v11.i32.7806
Published online Nov 16, 2023. doi: 10.12998/wjcc.v11.i32.7806
Table 1 Postoperative nausea and vomiting grading scale
PONV grade | Patient response |
0 | Without PONV |
I | Nausea without vomiting |
II | Nausea with vomiting (< 3 times/d) |
III | Vomiting ≥ 3 times/d |
Table 2 Comparison of baseline characteristics between the sufentanil and butorphanol groups
Sufentanil group (n = 55) | Butorphanol group (n = 55) | P value | |
Age | 71.0 ± 5.7 | 69.6 ± 5.7 | 0.199 |
Gender (male/female) | 32/23 | 34/21 | 0.698 |
ASA (I/II/III) | 0/33/22 | 0/30/25 | 0.847 |
Weight (kg) | 63.6 ± 10.3 | 68.6 ± 11.3 | 0.058 |
BMI (kg/m2) | 21.1 ± 1.8 | 20.81 ± 1.7 | 0.403 |
Smoking (yes/no) | 25/30 | 26/29 | 0.703 |
PONV or motion sickness history (yes/no) | 14/41 | 20/35 | 0.218 |
Operation time (h) | 3.41 ± 1.30 | 3.25 ± 1.07 | 0.484 |
Intraoperative infusion volume (mL) | 1290.9 ± 404.7 | 1243.6 ± 316.8 | 0.497 |
Postoperative 24-h infusion volume (mL) | 2380.9 ± 137.6 | 2342.7 ± 133.8 | 0.143 |
Postoperative 48-h infusion volume (mL) | 2152.7 ± 128.9 | 2125.5 ± 117.4 | 0.249 |
Table 3 Comparison of hemodynamics between the sufentanil and butorphanol groups
HR (BPM) | SBP (mmHg) | DBP (mmHg) | |||||||
Sufentanil | Butorphanol | P value | Sufentanil | Butorphanol | P value | Sufentanil | Butorphanol | P value | |
Pre-operation | 69.2 ± 9.0 | 67.9 ± 7.1 | 0.400 | 145.2 ± 15.2 | 146.1 ± 12.0 | 0.748 | 67.8 ± 6.2 | 67.51 ± 5.1 | 0.828 |
One minute before induction | 70.2 ± 9.5 | 68.8 ± 6.5 | 0.348 | 149.5 ± 17.9 | 149.3 ± 12.4 | 0.966 | 71.2 ± 8.8 | 68.4 ± 5.4 | 0.056 |
One minute after tracheal intubation | 69.8 ± 9.2 | 68.8 ± 6.1 | 0.480 | 144.3 ± 18.4 | 147.8 ± 10.5 | 0.233 | 69.5 ± 8.7 | 67.6 ± 4.3 | 0.156 |
Intraoperative maintenance | 67.3 ± 8.1 | 68.5 ± 6.3 | 0.388 | 145.2 ± 13.9 | 149.1 ± 9.8 | 0.098 | 68.3 ± 7.6 | 68.1 ± 4.5 | 0.867 |
Table 4 Comparison of postoperative nausea and vomiting within postoperative 48 h between the sufentanil and butorphanol groups
Table 5 Comparison of actual doses of propofol and remifentanil, agitation scores, Bruggrmann comfort scale scores, and effective compressions of patient-controlled intravenous analgesia pump
Sufentanil group (n = 55) | Butorphanol group (n = 55) | Z | P value | |
Propofol (mg) | 1027.2 ± 461.6 | 1016.4 ± 379.4 | - | 0.893 |
Remifentanil (mg) | 1.3 ± 0.6 | 1.2 ± 0.5 | - | 0.438 |
Agitation score (0/1/2/3) | 42/8/5/0 | 47/6/2/0 | -0.774 | 0.439 |
BCS score (0/1/2/3/4) | 6/5/30/14/0 | 1/4/24/25/1 | -2.195 | 0.028a |
Effective compressions of PCIA | 1.00 (2.00-1.00) | 1.00 (2.00-1.00) | - | 0.881 |
- Citation: Xie F, Sun DF, Yang L, Sun ZL. Effect of anesthesia induction with butorphanol on postoperative nausea and vomiting: A randomized controlled trial. World J Clin Cases 2023; 11(32): 7806-7813
- URL: https://www.wjgnet.com/2307-8960/full/v11/i32/7806.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v11.i32.7806