Value of ultrasound and magnetic resonance imaging combined with tumor markers in the diagnosis of ovarian tumors

Table 1 Ultrasonographic characteristics of benign and malignant tumors

	Echo		Capsule		Blood flow resistance index	Form		Blood flow signal display rate
	Rules	Irregularity	Yes	No		Clear	Not clear
Benign tumor	55	5	46	14	0.79 ± 0.05	54	6	15 (25%)
Malignant tumor	8	42	12	38	0.44 ± 0.49	5	45	50 (100%)
χ2/t	63.809		30.350		24.010	70.189		63.462
P value	0.000		0.000		0.000	0.000		0.000

Table 2 Comparison of apparent diffusion coefficient value (mm²/s) and time-signal intensity curve image features [n (%)] between benign and malignant tumors

	Solid part ADC value	ADC value of cystic part	TIC image features
			I type	II type	III type
Benign tumor	1789.74 ± 122.53	2799.33 ± 89.88	46 (76.67)	14 (23.33)	0 (0.00)
Malignant tumor	867.67 ± 15.87	2260.03 ± 91.75	0 (0.00)	4 (0.08)	46 (92.00)
χ2/t	33.353	20.615	65.885	4.685	94.875
P value	0.000	0.000	0.000	0.030	0.000

ADC: Apparent diffusion coefficient; TIC: Time-signal intensity curve.

Table 3 Serum tumor markers in patients with benign and malignant tumors

	n	CA125 (U/mL)	HE4 (pmol/L)
Benign tumor	60	22.67 ± 4.57	75.33 ± 9.84
Malignant tumor	50	397.60 ± 180.02	298.70 ± 40.66
t		-11.462	-28.982
P value		0.000	0.000

CA125: Carbohydrate antigen 125; HE4: Human epididymis protein 4.

Table 4 Comparison of diagnostic results and pathological results of three examination methods for ovarian tumors

	n	US		MRI		Tumor marker		Joint detection method
		Benign	Malignant	Benign	Malignant	Benign	Malignant	Benign	Malignant
Benign tumor	60	48	12	51	9	49	11	59	1
Malignant tumor	50	12	38	8	42	4	46	0	50
Total	110	60	50	59	51	53	57	59	51

US: Ultrasound; MRI: Magnetic resonance imaging.

Table 5 Comparison of diagnostic efficiency of different methods

Method	Diagnostic accuracy (%)	Diagnostic sensitivity (%)	Diagnostic specificity (%)
US	78.18 (86/110)	80.00 (48/60)	76.00 (38/50)
MRI	84.55 (93/110)	85.00 (51/60)	84.00 (42/50)
Tumor marker	86.36 (95/110)	81.67 (49/60)	92.00 (46/50)
Joint detection method	99.09 (109/110)	98.33 (59/60)	100.00 (50/50)
χ2	22.705	16.590	30.303
P value	0.000	0.001	0.000

US: Ultrasound; MRI: Magnetic resonance imaging.