Copyright
©The Author(s) 2023.
World J Clin Cases. Jan 26, 2023; 11(3): 610-620
Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.610
Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.610
Table 1 Demographic and clinical characteristics of patients in the different groups
Groups | n | Age (yr) | Gender (M/F) | BMI (kg/m2) | ASA (I/II) | Operation time (min) |
Group C | 38 | 55.9 ± 4.3 | 18/20 | 21.8 ± 1.4 | 26/12 | 12 (10-14) |
Group B1 | 36 | 56.9 ± 4.2 | 17/19 | 21.3 ± 1.4 | 24/12 | 11 (10-12) |
Group B2 | 32 | 56.6 ± 4.8 | 15/17 | 21.2 ± 1.3 | 21/11 | 11 (10-12) |
P value | 0.591 | 0.999 | 0.200 | 0.969 | 0.218 |
Table 2 Comparison of median effective concentration, dose for anesthesia, and awakening concentration of propofol among the different groups
Groups | n | EC50 (μg/mL) | 95%CI (μg/mL) | Amount of propofol necessary for anesthesia (mg) | Awakening concentration of propofol (μg/mL) |
Group C | 38 | 4.05 | 3.78-4.34 | 151.0 (142.0-160.5) | 1.200 (0.975-1.300) |
Group B1 | 36 | 3.411 | 3.20-3.62 | 142 (135-154)1,3 | 1.200 (1.025-1.500)3 |
Group B2 | 32 | 3.031,2 | 2.83-3.23 | 132.00 (125.00-144.75)1,2 | 1.1 (0.9-1.2)2 |
Table 3 Comparison of mean arterial pressure and heart rate among the different groups
Groups | T0 | T1 | T2 | T3 | |
MAP (mmHg) | Group C | 90.4 ± 6.1 | 73.4 ± 6.11 | 77.0 ± 5.81 | 88.6 ± 5.4 |
Group B1 | 89.4 ± 5.4 | 81.7 ± 4.1 | 85.3 ± 4.0 | 88.3 ± 3.8 | |
Group B2 | 89.5 ± 5.1 | 78.3 ± 5.02 | 82.4 ± 4.22 | 88.5 ± 4.1 | |
HR (bpm) | Group C | 81.8 ± 8.8 | 68.8 ± 7.21 | 72.1 ± 6.9 | 79.9 ± 6.0 |
Group B1 | 80.3 ± 9.0 | 73.2 ± 8.5 | 74.9 ± 8.0 | 78.3 ± 6.2 | |
Group B2 | 81.9 ± 9.3 | 74.7 ± 9.8 | 76.2 ± 8.2 | 80.1 ± 6.1 |
Table 4 Comparison of frequency of adverse events in perianesthesia among the different groups
Groups | n | Hypoxemia | Sinus bradycardia | Hypotension | Nausea, vomiting | Vertigo |
Group C | 38 | 5 (13.2%) | 1 (2.6%) | 1 (2.6%) | 2 (5.3%) | 4 (10.5%) |
Group B1 | 36 | 2 (5.6%) | 0 (0%) | 0 (0%) | 1 (2.8%) | 3 (8.3%) |
Group B2 | 32 | 3 (9.4%) | 2 (6.3%) | 0 (0%) | 2 (6.3%) | 3 (9.4%) |
- Citation: Guo F, Sun DF, Feng Y, Yang L, Li JL, Sun ZL. Efficacy and safety of propofol target-controlled infusion combined with butorphanol for sedated colonoscopy. World J Clin Cases 2023; 11(3): 610-620
- URL: https://www.wjgnet.com/2307-8960/full/v11/i3/610.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v11.i3.610