Factors influencing the surveillance of re-emerging intracranial infections in elective neurosurgical patients: A single-center retrospective study

Table 1 Comparison of clinical data, n = 94

Projects	Infection group, n = 45	Control group, n = 49	Test value	P value
Age (mean ± SD)	47.867 ± 15.286	52.816 ± 15.073	1.580a	0.118
Male	23 (57.5)	17 (42.5)	2.586b	0.108
Weight [kg, M (P25, P75)]	65 (58, 75)	64 (57, 68.5)	-1.251c	0.211
Time of surgery [mo, M (P25, P75)]	7 (4, 10)	7 (3, 9)	-0.951c	0.341
First unit	24 (53.3)	24 (49.0)	0.178b	0.673
Systolic pressure [mmHG, M (P25, P75)]	144 (126, 160)	126 (120, 137)	-3.526c	< 0.001
Diastolic pressure [mmHG, M (P25, P75)]	80.0 (70.0, 83.0)	80.0 (72.5, 90.0)	-1.345c	0.179
History of hypertension	28 (57.1)	8 (17.8)	15.383b	< 0.001
Supratentorial craniotomy	32 (71.1)	44 (89.8)	5.290b	0.021
Postoperative body temperature [C, M (P25, P75)]	38.10 (37.72, 38.50)	37.40 (36.75, 37.80)	-5.471c	< 0.001
Admission WBC [109, M (P25, P75)]	7.98 (6.67, 10.88)	7.52 (5.19, 9.60)	-1.557c	0.119
First postoperative WBC [109, M (P25, P75)]	14.22 (11.08, 16.70)	12.78 (10.13, 15.17)	-2.030c	0.042
Discharge WBC [× 109/L, M (P25, P75)]	8.67 (6.59, 11.30)	8.36 (6.89, 9.91)	-0.701c	0.483
Intraoperative blood loss [mL, M (P25, P75)]	30 (30, 350)	100 (30, 250)	-0.090c	0.929
Intraoperative blood transfusion	12.0 (26.6)	6.0 (12.2)	2.525b	0.112
Duration of surgery [h, M (P25, P75)]	3.90 (3.00, 5.42)	3.40 (2.45, 5.00)	-1.261	0.207
With artificial implants	45(100)	43(87.8)	3.419 b	0.064
Reduction of bone flap	39 (86.7)	47 (95.9)	2.579b	0.108

^at value.

^bχ² value.

^cU value.

Data are n (%). M (P₂₅, P₇₅): Median (Interquartile range, Q3-Q1); SD: Standard deviation; WBC: White blood cell count.

Table 2 Multifactorial analysis of patients with postoperative reinfection, n = 94

Projects	Β value	Standard error	Wald value	OR value	95%CI	P value
History of hypertension	1.827	0.630	8.403	6.214	1.807-21.370	0.004
Supratentorial craniotomy	0.679	0.767	0.784	1.972	0.439-8.869	0.367
Postoperative body temperature	2.536	0.598	17.986	0.078	3.913-40.795	< 0.001
First postoperative WBC	0.061	0.061	1.004	1.063	0.943-1.119	0.316

Systolic blood pressure and normal blood pressure were covariates, and systolic blood pressure was included in the multifactorial analysis. CI: Confidence interval; OR: Odds ratio; WBC: White blood cell count.