Non-retroareolar male mucinous breast cancer without gynecomastia development in an elderly man: A case report

Table 1 Clinical case characterization

Ref.	Country	Age (yr)	Case history (yr)	Laterality	Past history	Tumor max-diameter	Tumor location	Pathology characteristic	Lymphatic metastasis	ER	PR	HER2/CerbB-2	KI67 %	BRCA	Surgery	Adjuvant therapy	DFS (mo)
Fujikawa et al[20], 1998	Japan	35	2	Right	Negative	80	Areola	M	Negative	Positive	Positive	None	None	None	MRM	C + TAM	30
Peschos et al[19], 2008	Greece	83	None	Left	None	70	Areola	M	None	Positive	Positive	None	None	None	MRM	C + TAM	None
Hammedi et al[10], 2010	Tunisia	75	2 mo	Right	Negative	40	Areola	M	Positive + 2	Negative	Positive	Negative	None	None	MRM	C + R + TAM	36
Dragoumis et al[21], 2012	Greece	59	1	Right	Negative	30	Areola	M	Positive	Positive	Positive	Negative	None	None	MRM	C + R + TAM	74
Imakado and Masuda[22], 2012	Japan	72	3	Left	Negative	20	Areola-aside	M	Positive	Positive	Positive	None	None	None	MRM	TAM	60
Gupta et al[18], 2015	India	73	8	Right	Negative	95	Areola	M	Negative	Positive	Positive	Middle 2	11	None	MRM	TAM	8
Kim and Lee[8], 2021	Korean	78	1	Left	Negative	35	Areola	M + B-cell	Positive + 2	None	None	None	None	Negative	MRM	C + TAM	11
Takahashi et al[17], 2021	Japan	75	None	Right	Sister breast cancer	13	Axilla	M + IDC	Negative	Positive	Positive	Negative	33	Negative	MRM	TAM	24
Ahmed et al[9], 2022	United States	74	1	Left	Thyroid cancer	18	Areola	M	Negative	None	None	None	None	None	MRM	TAM	48

ER: Estrogen receptor; PR: Progesterone receptor; BRCA: Breast cancer susceptibility gene; DFS: Disease free survival; TAM: Tamoxifen; MRM: Modified radical mastectomy; M: Mastectomy; C: Chemotherapy; R: Radiotherapy.