Clinicopathological study of malignant peripheral nerve sheath tumors in the head and neck: Case reports and review of literature

Table 1 Clinicopathological characteristics of malignant peripheral nerve sheath tumor arising in the head and neck

Case	Sex/age	Location	Size (cm)	Treatment	Recurrence (site)	Survival	Follow-up (months)	H3K27Me3
1	F/62	Anterior maxilla	2.5	S+R+C	DR (lung, bone)	Yes	28	Positive
2	F/28	Left mandible	3	S+R+C	NR	Yes	24	Positive
3	M/22	Right submandibular region	2.5	S	/	/	/	Complete loss
4	M/74	Gingival and the left cheek and left temporal	2.5	S	/	/	/	Positive
5	F/48	Mandible	3	S+R+C	LR, DR (lung)	No	70	Positive
6	M/40	Left facial and upper left gingiva	3	S+R	LR, DR (trunk, brain)	No	216	Partial loss
7	F/40	Right mandible	3	S	/	/	/	Partial loss
8	F/44	The left inferior temporal fossa	4.5	R+C	NR	No	13	Partial loss
9	M/58	Right palat	1.5	S	NR	Yes	74	/
10	M/75	Mandibular gingival	3	S	DR (lung, lymph node)	No	24	Positive

S: Surgery; R: Radiotherapy; C: Chemotherapy; LR: Local recurrence; DR: Distant recurrence; NR: No recurrence.

Table 2 A review of malignant peripheral nerve sheath tumor cases arising in the maxilla

Ref.	Patients (n)	Sex	Age	Treatment	Follow-up (mon)	Recurrence	NF association
Kameyama et al[27], 1987	1	F	61	/	/	/	No
Urade et al[28], 1990	1	F	47	S+R+C	22	Died of disease	No
Che et al[19], 2006	1	F	13	R	/	/	No
Patil et al[29], 2007	1	M	45	/	/	/	No
Janardhanan et al[30], 2011	1	M	40	S	/	Died of disease	Yes
Ali et al[31], 2011	1	M	50	R	8	No	/
Tamgadge et al[32], 2014	1	M	65	/	/	/	No
Neetha et al[33], 2004	1	F	12	R	/	/	/
Muraki et al[34], 1999	1	M	43	R+C	20	Died of disease	Yes
Present study	1	F	62	S+R+C	28	Yes	No

S: Surgery; R: Radiotherapy; C: Chemotherapy; NF: Nuclear factor.