Malignant melanoma of the prostate: Primary or metastasis? A case report

Table 1 Clinicopathological characteristics of the 10 primary prostatic melanomas included in the present review

Ref.	Age	History disease	Symptoms	Other test	Treatment	Stage	Time to recurrence	Metastases	Secondly treatment	OS
Berry and Reese[4], 1953	38	No	Luts	n/m	Cystoprostatectomy	n/m	7 mo	n/m	n/m	36 mo
Hübler et al[5], 1980	n/f	n/f	n/f	n/f	n/f	n/f	n/f	n/f	n/f	n/f
Wang[6], 2001	61	n/m	BPH	(1) Physical examination of the whole body skin surface, oral cavity, and mucosa and optic fundus; (2) CT and MRI of the brain, abdo_x005f men and pelvic cavity; and (3) endoscopy of gastrointestinal tract	TURP	T1N0Mo	n/m	n/m	No	84 mo
Wong and Bell[8], 2006	71	n/f	Urinary retention	n/f	TURP	n/f	n/f	n/f	n/f	5 mo
Wong et al[7], 2008	n/f	n/f	n/f	n/f	n/f	n/f	n/f	n/f	n/f	n/f
Doublali et al[9], 2010	75	n/m	Urinary tract obstruction. Urethroscopy had revealed black discoloration of the prostate	(1) Physical examination of body skin surface, mucosa; (2) CT of brain, abdomen and pelvis; and (3) colonoscopy and gastroscopy	TURP	n/m	n/m	n/m	No	1 mo
Ma et al[10], 2010	29	n/m	Disuria Digital rectal examination and Transrectal Ultrasound of a mass	Pelvic CT scan with contrast	Radical prostatectomy	T2N0M0	n/m	n/m	n/m	3 mo
Tosev et al[11], 2015	37	Hodgkin’s disease	Hematuria and urinary retention. In-house cystoscopy showed an asymmetric prostate enlargement with purple discoloration Prostate biopsy	(1) Skin of the body; (2) colonoscopy and gastroscopy; (3) CT of chest and abdomen; and (4) pelvic MRI	Open retropubic radical prostatectomy with extended lymph-node dissection	n/m	4 mo	Lung	Dacarbazine, ipilimumab, nivolumab	16 mo
Li et al[12], 2019	42	No	Hematuria Accepy PVP. Intraoperatively, a dark lesion was noted in the patient’s prostatic urethra	(1) CT of the chest, abdomen, and pelvis; (2) brain MRI; (3) bone scan; and (4) 18F-FDG PET/CT scan	RRP and PLND	T2N1M0	3 mo	Lesion along the right iliac artery, pulmonary nodule	Biochemotherapy for 6 cycles dacarbazine, vinblastine, cisplatin, IL2	84 mo
Parmar et al[13], 2019	65	No	Acute urinary retention	(1) Physical examination of whole body skin surface, oral cavity and anal mucosa; and (2) PET-CT	TURP, Dacarbazine, Chemotherapy	n/m	3 mo	n/m	n/m	n/m

n/f: Full text not found; n/m: Not mentioned; no: None; LUTS: Lower urinary tract symptoms; TURP: Transurethral resection of the prostate; PVP: Photoselective vaporization of the prostate; RRP: Radical retropubic prostatectomy; PLND: Pelvic lymph node dissection; MRI: Magnetic resonance imaging; ¹⁸F-FDG PET/CT: 18F-fluorodeoxyglucose positron emission tomography computed tomography; IL: Interleukin.