Next-generation sequencing technology for the diagnosis of Pneumocystis pneumonia in an immunocompetent female: A case report

Table 1 Main inflammatory parameters

Item	Result on admission	Results at ICU	Reference range
WBC (× 109)	4.31	2.64	3.5-10
RBC (× 1012)	2.49	2.10	3.5-5.5
HGB (g/L)	84	69	114-163
NEUT (× 109)	3.65	2.42	1.8-6.3
%NEUT	84.8	91.7	40-75
MONO (× 109 )	0.04	0.04	0.1-0.6
%MONO	0.9	1.5	3-10
LYMBP (× 109)	0.60	0.17	1.1-3.2
%LYMBP	13.9	6.4	20-50
PLT (× 109)	114	69	125-350
CRP (mg/L)	7.51	37.69	0-5
ESR (mm/h)	47	120	0-20
PCT (ng/mL)	0.75	> 100	0-0.046
IL-6 (pg/mL)	6.33	33.64	< 7
G test (pg/mL)	572.42		< 60

ICU: Intensive care unit; WBC: White blood cells; RBC: Red blood cells; HGB: Hemoglobin; NEUT: Neutrophils; MONO: Monocytes; LYMBP: Lymphocytes; PLT: Platelets; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; PCT: Procalcitonin; IL-6: Interleukin-6; G test: (1-3)-β-D-glucan test.

Table 2 Liver and renal function results

Item	Result on admission	Results at ICU	Reference range
TBIL (μmol/L)	12.8	64.9	3.6-20.5
TP (g/L)	65.3	46.3	65-85
ALB (g/L)	37.3	22.2	40-55
ALT (U/L)	42	61	9-50
AST (U/L)	37	39	15-40
sCrea (μmol/L)	76	307	57-97
Urea (mmol/L)	8.53	31.25	3.1-8
UA (μmol/L)	314	629	210-420
LDH(U/L)	852		94-250

Blood was collected for liver and renal function. ICU: Intensive care unit; TBIL: Total bilirubin; TP: Total protein; ALB: Serum albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; sCrea: Serum creatinine; UA: Uric acid; LDH: Lactate dehydrogenase.

Table 3 Next-generation sequencing gene detection of bronchoalveolar lavage fluid

Genus	Number of sequences	Species	Number of sequences
Pneumocystis	12297	Pneumocystis jirovecii	12152