Malignant transformation of pulmonary bronchiolar adenoma into mucinous adenocarcinoma: A case report

Table 1 Clinicopathological features of patients with malignant transformation of bronchiole adenoma/ciliated muconodular papillary tumors

Ref.	Age (yr)/Sex	Size (mm)	Location	Diagnosis	Malignant transformation	Gene mutation
Miyai et al[2], 2018	67/F	20	Middle lobe of the right lung	CMPT	Invasive spindle cell carcinoma	/
Chen et al[3], 2021	61/M	14	Inferior lobe of the right lung	CMPT	MA	-
Han et al[4], 2021	70/M	15	Middle lobe of the right lung	BA	MA	KRAS (G12V)
Wang et al[5], 2021	67/F	7	Dorsal segment of the left lung	BA	Adenocarcinoma	CCNE1, HER2
Present study	56/F	17	Inferior lobe of the left lung	BA	MA	/

F: Female; M: Male; “-”: No mutation detected; “/”: Not tested; CMPT: Ciliated muconodular papillary tumors; BA: Bronchiole adenoma; MA: Mucinous adenocarcinoma.