Extraskeletal Ewing sarcoma of the stomach: A rare case report

Table 1 Clinical characteristics and outcomes in reported cases of gastric Ewing’s sarcoma

Ref.	Age in yr, sex	Clinical presentation	Location	Tumor size in cm	Immunohistochemistry	Molecular genetic detection	Distant metastasis	Neoadjuvant chemotherapy	Surgery	Postoperative chemotherapy	Follow-up in mo	Outcome
Czekalla et al[6], 2004	14, M	Anorexia, epigastric pain	Anterior wall body	5	CD99, CD117, S100, vimentin, neurofilament, NSE	t(11;22)(q24;q12)	Liver	Yes	SG	No	24	Alive
Soulard et al[7], 2005	66, F	Epigastric pain	Antrum	8	CD99, S100, NSE, vimentin	t(21;22)(q22;q12)	No	No	Gastrectomy	Yes	10	Dead
Colovic et al[8], 2009	44, F	Epigastric pain	Posterior wall body	10	CD99, S100, vimentin, NSE, PGP9.5	NA	No	No	Excision	No	20	Alive
Rafailidis et al[9], 2009	68, M	Abdominal pain, dyspepsia, weakness	Body	12	vimentin, NSE, CD99, CD117, Leu-7	t(11;22)(q24;q12)	Liver	No	SG	Yes	13	Dead
Inoue et al[10], 2011	41, F	Abdominal pain	Anterior wall body	9	CD99, vimentin, CD117, S100, chromogranin A, synaptophysin	t(11;22)(q24;q12)	Enterocoelia	No	DG	Yes	110	Dead
Kim et al[11], 2012	35, F	No special symptoms	Antrum	5.5	CD99, synaptophysin	NA	No	No	WR	No	11	Alive
Song et al[12], 2016	55, M	Upper abdominal pain	vomiting High body	6.5	CD99, FLI1, chromogranin	EWS-FLI1 fusion transcript	Lymph nodes	No	TG	Yes	13	Alive
Kumar et al[13], 2016	32, F	Epigastric pain	Lesser curvature	11	CD99, vimentin, S100	NA	No	No	Excision	Yes	12	Alive
Khuri et al[14], 2016	31, F	Upper gastrointestinal hemorrhage	Lesser curvature	11	CD99, FLI1, vimentin, Ki67	(11;22 translocation)	Pancreas Splenic hilum	No	TDPSLA	No	36	Alive
Maxwell et al[15], 2016	66, F	Anemia, abdominal pain	Antrum	11	NA	EWSR1 gene rearrangement	No	No	DG	Yes	NA	NA
Hopp et al[4], 2019	24, M	Abdominal pain, nausea, vomiting	Posterior wall	10	keratin OSCAR/ AE1/AE3, CD99	NA	NA	Yes	DG	NA	NA	NA
Ye et al[1], 2021	55, M	fatigue and fever, lose weight	posterior wall	7.5	CD99, CD57, CD56, vimentin	NA	No	No	DG + Roux-en-Y	No	8	Alive

CG: Curative gastrectomy; DG: Distal gastrectomy; NA: Not available; RDG + Roux-en-Y: Distal gastrectomy + Roux-en-Y gastrojejunostomy; SG: Subtotal gastrectomy; TG: Total gastrectomy; TDPSLA: Total gastrectomy + distal pancreatectomy + splenectomy + left adrenalectomy; WR: Wedge resection.