Esophageal myoepithelial carcinoma: Four case reports

Table 1 Clinical and pathological factors of four esophageal myoepithelial carcinoma patients

Case	1	2	3	4
Sex	M	M	M	F
Age (year)	57	60	79	81
Complaint	Dysphagia	Dysphagia	Dysphagia	Retrosternal discomfort
Location	Middle	Middle	Middle	Lower
Depth	Muscle layer	Submucosa	Whole layer	Whole layer
Size (cm)	4.5 × 4.0 × 1.2	3.0 × 2.0 × 1.5	3.5 × 2.8 × 2.0	2.9 × 1.7 × 0.7
Tumor marker	TAP (+)	TAP (+)	Normal	Normal
Node involvement	+	–	–	–
Cytology	MC + SCC	MC + SCC	MC	MC
Therapy	R	R	R	R
Follow up	Died from unknown cause	Lost to follow-up	Anastomosis recurrence and lung metastases	NED

F: Female; M: Male; MC: Myoepithelial carcinoma; SCC: Squamous cell carcinoma; TAP: Tumor abnormal protein; R: Radical surgery; NED: No evidence of disease +, yes/present/positive; –: No/absent/negative.

Table 2 Immunohistochemistry of four esophageal myoepithelial carcinoma patients

Case	SOX-10	P63	CK5/6	CK8/18	Ki-67	AE1/AE3	P40	Calponin	S-100	CK7	CD56
1	+	+	+	+	> 70%	+	+	-	-	-	+
2	+	+	+	-	> 60%	+	+	+	+	+	-
3	+	+	-	+	> 70%	-	-	+	+	-	-
4	-	+	+	+	> 70%	+	+	+	-	-	-

+: Yes/present/positive; –: No/absent/negative.

Table 3 Computed tomography image features of the four esophagus myoepithelial carcinoma patients

case	1	2	3	4
Morphological subtype	Medullary	Fungating	Ulcerative	Fungating
Length (mm)	49	96	55	45
Enhancement degree	Homogeneous	Heterogeneous	Heterogeneous	Homogeneous
Enhanced homogeneity	Mild	Marked	Mild	Mild
Enlarged lymph node	–	+	–	–
Cystic change /necrosis	–	+	+	–
Ulceration	–	+	–	–

+: Yes/present/positive; –: No/absent/negative.