Observational Study
Copyright ©The Author(s) 2022.
World J Clin Cases. Mar 26, 2022; 10(9): 2783-2791
Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2783
Table 1 Relationship between Ubiquilin4 protein expression and clinicopathological features in 117 cases of cervical cancer
VariablesUBQLN4 expression
Total
Χ2
P value
Low
High
Age (yr)0.7130.398
≤ 453424 (41.4%)58
> 453029 (49.2%)59
Null
Pathologic type0.2440.885
AD21 (33.3%)3
ASC32 (40.0%)5
SCC5950 (45.9%)109
Lymph node metastasis0.2420.623
No5342 (44.2%)95
Yes1111 (50.0%)22
Histological grade1.5180.279
I/II1612 (42.9%)28
III3950 (56.2%)89
FIGO stage (2018)0.2420.623
I/II5342 (44.2%)95
III1111 (50.0%)22
Table 2 Univariate and multivariate analyses of the factors correlated with overall survival and disease-free survival
Clinical variablesUnivariate analysis (PFS)
Multivariate analysis (PFS)
Univariate analysis (OS)
Multivariate analysis (OS)
HR
95%CI
P value1
HR
95%CI
P value1
HR
95%CI
P value
HR
95%CI
P value1
UBQLN4 (low vs high)3.0261.524-6.0060.0022.2611.115-4.5830.0244.3571.962-9.67902.931.284-6.6830.011
Age (≤ 45 vs > 45)4.9442.261-10.80904.3311.953-9.60507.1712.763-18.61105.9272.241-15.6780
Grade (I/II vs III)1.8190.805-4.1080.152.4440.913-6.5420.075
FIGO stage (I/II vs III)2.8691.983-4.15102.6591.807-3.91103.3722.234-5.08903.0481.968-4.720