Park S, Ryu HS, Lee JK, Park SS, Kwon SJ, Hwang WM, Yun SR, Park MH, Park Y. Acute kidney injury due to intravenous detergent poisoning: A case report. World J Clin Cases 2022; 10(6): 2036-2044 [PMID: 35317142 DOI: 10.12998/wjcc.v10.i6.2036]
Corresponding Author of This Article
Yohan Park, MD, Assistant Professor, Department of Internal Medicine, Division of Nephrology, Konyang University Hospital, College of Medicine, Gwanjeodong-ro 158, Seo-gu, Daejeon 35365, South Korea. nofever38@kyuh.ac.kr
Research Domain of This Article
Urology & Nephrology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Feb 26, 2022; 10(6): 2036-2044 Published online Feb 26, 2022. doi: 10.12998/wjcc.v10.i6.2036
Table 1 Detergent composition and molecular weight
Ingredients
Molecular weight (g/moL)
Dodecyldimethylamine oxide
229.40
Sodium alkylbenzene sulfonate
334.45
Water
18.02
Ethanol
46.07
Octane-1,2-diol
146.23
Sodium sulfate
142.04
Silicon dioxide
60.08
Sodium hydrogen carbonate
84.01
Dimethylsiloxane
92.17
Calcium carbonate
100.09
2,6-dimethyl-7-octen-2-ol
156.27
Linalool
154.25
(E)-dodec-2-en-1-al
182.30
(R)-p-mentha-1,8-dien
136.23
Table 2 Complete blood cell count and serum chemistry findings until 3rd day of hospitalization
Parameters
1st day of hospitalization
2nd day of hospitalization
3rd day of hospitalization
WBC (× 103/μL)
14.8
9.9
6.5
Hb (g/dL)
12.6
10.1
10.7
PLT (× 103/μL)
149
109
110
BUN (mg/dL)
23.7
44.0
55.7
Cr (mg/dL)
0.99
3.59
5.42
AST (IU/L)
111
51
31
ALT (IU/L)
22
8
4
Total bilirubin (mg/dL)
3.48
0.84
0.57
Direct bilirubin (mg/dL)
1.02
-
-
LDH (IU/L)
1726
833
731
CPK (IU/L)
56
-
36
Ca (mg/dL)
9.61
9.06
9.10
Inorganic P (mg/dL)
3.77
5.16
4.59
Na (mEq/L)
139
136
137
K (mEq/L)
3.76
3.82
4.02
CI (mEq/L)
104.2
103.1
103.7
Total CO2 (mmol/L)
25.1
22.9
22.5
Table 3 Urine dipstick test results and urine microscopic findings at the emergency department
The dipstick urinalysis findings
Color
Orange
Turbidity
Cloudy
Specific gravity
1.044
pH
6.5
Protein
3+
Glucose
-
Ketone
-
Blood
3+
Urobilinogen
-
Bilirubin
-
Nitrite
-
WBC
-
Urine microscopy findings
Micro RBC (/HPF)
Many (> 20)
Micro WBC (/HPF)
0-2
Micro sediment
No cast and crystal
Table 4 Laboratory tests for hemolysis on the 2nd day of hospitalization
Tests
2nd day of hospitalization
Peripheral blood smear
RBC
Normocytic and normochromic RBCs with mild anisopoikilocytosis
WBC
Normal WBC counts with no toxic granulation and vacuolations
PLT
Decreased PLT counts
Reticulocyte count (%)
1.6
Hemosiderin stain
Negative
Haptoglobin (mg/dL)
45
Homocysteine (μmol/L)
8.66
Citation: Park S, Ryu HS, Lee JK, Park SS, Kwon SJ, Hwang WM, Yun SR, Park MH, Park Y. Acute kidney injury due to intravenous detergent poisoning: A case report. World J Clin Cases 2022; 10(6): 2036-2044