Cryptogenic organizing pneumonia associated with pregnancy: A case report

Table 1 Characteristics of cryptogenic organizing pneumonia with pregnancy: Previous published case report

Case No.	1	2	3	4
Ref.	Ghidini et al[1], 1999	Futagami et al[10], 2003	Holder et al[5], 2011	Present
Age (yr)	27	33	16	35
Underlying disease	HIV	ITP, asthma	COP, pulmonary hypertension, asthma, partial right lower-lobe resection	None
Gestational age (wk) at diagnosis	26 + 5	38	20	16 + 1
Gestational age (wk) at delivery	34	38	28	39+4
Symptoms	Cough, dyspnea, chest pain	Cough, fever	Dyspnea, chest pain, fatigue	Chest pain, cough, dyspnea, sputum
Radiologic Findings	Diffuse bilateral parenchymal infiltrates (left lower lobe) in chest X-ray	Diffuse bilateral parenchymal infiltrates in chest X-ray	Patchy ground glass infiltrates in chest CT	Multifocal patchy airspace consolidation and GGO
Initial diagnosis	Asthmatic bronchitis or interstitial; Pneumonia	Asthmatic bronchitis or mycoplasmic pneumonia	Pre-existing COP	CAP
Definite diagnosis method	Open lung biopsy	BAL, TBLB	NA	BAL, TBLB
Initial treatment	Trimethoprim (300 mg) + sulfamethoxazole (1500 mg) IV every 6 h + ceftriaxone (2 g) IV daily, methylprednisolone, 60 mg IV every 8 h	Cefmetazole 1 g every 12 h + gabexatemesilate 2 g IV continuously	NA	Ceftriaxone (2 g daily) IV + amoxicillin (250 mg every 8 h), cefpodoxime (100 mg every 12 h) orally
Final treatment	Dexamethasone, 5 mg IV every 12 h for 72 h, folowed by methylprednisolone, 60 mg IV daily for 48 h, then 30 mg IV every 8 h for 4 d; and prednisone 40 mg/d orally	Minocycline 100 mg + methylprednisolone 125 mg every 12 h and every 8 h, for 5 d, followed 40 mg per day orally for 11 d	Nebulizer of a beta-2 agonist and corticosteroids	Prednisolone (0.5 mg/kg/d) for 10 d

BAL: Bronchoalveolar lavage; CAP: Community acquired pneumonia; COP: Cryptogenic organizing pneumonia; GGO: Ground glass opacity; HIV: Human immunodeficiency virus; ITP: Immune thrombocytopenia; IV: Intravenous; NA: Not available; TBLB: Transbronchial lung biopsy; CT: Computed tomography.