Toxic epidermal necrolysis induced by ritodrine in pregnancy: A case report

Table 1 Symptoms and treatments of the patient in different periods

Date	Gestational week	Symptoms	Treatments
November 1, 2017	32 + 3 wk	Red skin rash on both lower limbs, accompanied by itching, no pain	None
November 4, 2017	32 + 6 wk	Red skin rash, lumps, and itching all over the body	Calamine lotion until recovery and mometasone furoate cream for 3 d externally
November 6, 2017	33 + 1 wk	Scattered red rash all over the body with itching	Prednisone 60 mg a day for 2 d p.o.
November 8, 2017	33 + 3 wk	Erythematous and bullous rashes spread to the entire body	Hydrocortisone 200 mg a day until delivery i.v.
November 9, 2017	33 + 4 wk	Rash on the right upper arm turned dark gray	Calcium gluconate 10 mL once i.v.
November 11, 2017	33 + 5 wk	Red skin rash, lumps, and itching all over the body, skin tingling	As above
November 12, 2017	34 wk	Skin rash on the upper extremities turned dark and gray with small blisters; the skin of the elbows was broken, the blisters became larger, and the body-wide rashes were accompanied by blisters; several white spots were seen on the tip of the tongue	Methylprednisolone 60 mg i.v.g once + immunoglobulin for 5 d + mupirocin ointment until recovery externally
November 13, 2017	34 + 1 wk	Symmetrical edema of the skin all over the body with dark red patches, unclear, tender, tongue mucosal ulcer	Cesarean section, methylprednisolone 40 mg i.v. twice a day for 1 wk