Manojlovic N, Savic G, Nikolic B, Rancic N. Dynamic monitoring of carcinoembryonic antigen, CA19-9 and inflammation-based indices in patients with advanced colorectal cancer undergoing chemotherapy. World J Clin Cases 2022; 10(3): 899-918 [PMID: 35127905 DOI: 10.12998/wjcc.v10.i3.899]
Corresponding Author of This Article
Nebojsa Manojlovic, PhD, Associate Professor, Clinic for Gastroenterology and Hepatology, Military Medical Academy, Faculty of Medicine of the Military Medical Academy, University of Defence, Crnotravska 17, Belgrade 11000, Serbia. nebojsa.manojlovic1@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Observational Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 5 Binary logistic regression, and univariate and multivariate analyses
Markers
Univariate logistic regression
Multivariate logistic regression
CEA
1.005 (1.002-1.008), P < 0.001
1.004 (1.000-1.007); P = 0.044
CA19-9
1.005 (1.001-1.008), P = 0.015
1.001 (0,998-1.004), P > 0.05
NLR
1.011 (1.004-1.018), P = 0.001
1.015 (0.996-1.034), P > 0.05
PLR
1.009 (1.001-1.018), P = 0.034
1.003 (0.986-1.021), P > 0.05
LMR
1.000 (0.993-1.007), P > 0.05
SII
1.006 (1.002- 1.010), P = 0.004
0.997 (0.985-1.009), P > 0.05
Table 6 Diagnostic characteristics of carcinoembryonic antigen, carbohydrate antigen, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and systemic immune-inflammation index
Citation: Manojlovic N, Savic G, Nikolic B, Rancic N. Dynamic monitoring of carcinoembryonic antigen, CA19-9 and inflammation-based indices in patients with advanced colorectal cancer undergoing chemotherapy. World J Clin Cases 2022; 10(3): 899-918