Concomitant Othello syndrome and impulse control disorders in a patient with Parkinson’s disease: A case report

Table 1 Clinical characteristics of 28 Parkinson’s disease patients with concomitant Othello syndrome and impulse control disorders

Ref.	Patient	Sex	Age at PD onset	Age at OS onset	PD duration at OS onset	ICDs	Dopamine agonist	Visual hall-ucinations	Psychiatry history	Neuroimaging	Dementia	Measures undertaken
Poletti et al[6]	Patient 1	M	45	60	15	PG + HS + BE	Pramipexole	Yes	N/A	N/A	No	N/A
Poletti et al[6]	Patient 2	M	50	62	12	HS + PG + DDS	Ropinirole	Yes	N/A	N/A	No	N/A
Poletti et al[6]	Patient 3	M	67	76	9	HS	Pramipexole	Yes	N/A	N/A	No	N/A
Poletti et al[6]	Patient 4	M	42	52	10	HS	Ropinirole	No	N/A	N/A	No	N/A
Poletti et al[6]	Patient 5	M	34	40	6	HS + PG	Pramipexole	No	N/A	N/A	No	N/A
Poletti et al[6]	Patient 6	M	48	58	10	HS	Ropinirole	Yes	N/A	N/A	No	N/A
Poletti et al[6]	Patient 7	M	61	72	11	HS	Pramipexole	Yes	N/A	N/A	No	N/A
Poletti et al[6]	Patient 8	M	57	65	8	PG + punding + HS	Ropinirole	Yes	N/A	N/A	No	N/A
Poletti et al[6]	Patient 9	M	47	52	5	HS + PG	Ropinirole	No	N/A	N/A	No	N/A
Cannas et al[8]	Patient 10	M	44	46	2	HS	Pergolide	No	Anxiety, depression	N/A	No	Reduced pergolide, added quetiapine
Cannas et al[9]	Patient 11	M	44	49	5	HS	Pergolide	No	N/A	Normal	No	Stopped pergolide, added quentiape
Adam et al[10]	Patient 12	M	38	39	1	HS + CS	Cabergoline	N/A	Hypomania	N/A	N/A	Stopped cabergoline, STN-DBS
Adam et al[10]	Patient 13	M	32	34	2	PG + DDS	Pergolide	N/A	No	N/A	N/A	Stopped pergolide, STN-DBS
Graff-Radford et al[11]	Patient 14	M	49	58	9	HS	Pramipexole	N/A	No	N/A	N/A	Stopped pramipexole
Graff-Radford et al[11]	Patient 15	M	39	42	3	HS + PG	Pramipexole	N/A	No	Normal	N/A	Stopped pramipexole
Graff-Radford et al[11]	Patient 16	F	53	64	11	CS	Pramipexole	N/A	Anxiety	Normal CT	N/A	Stopped prmipexole
Graff-Radford et al[11]	Patient 17	M	43	49	6	HS	Ropinirole	N/A	Depression	Normal	N/A	Stopped ropinirole
Graff-Radford et al[11]	Patient 18	M	50	56	6	HS + PG	Pramipexole	N/A	No	N/A	N/A	Stopped prmipexole
Graff-Radford et al[11]	Patient 19	F	43	56	13	HS	Pramipexole	N/A	Anxiety	Old right basal ganglia infarct	N/A	Reduced prmipexole
Graff-Radford et al[11]	Patient 20	M	49	51	2	HS + CS	Ropinirole	N/A	Anxiety	Normal	N/A	Stopped ropinirole
Foley et al[12]	Patient 21	M	51	NA	NA	HS	Ropinirole	Yes	N/A	mild left fronto-temporal atrophy	N/A	Reduced ropinirole
Foley et al[12]	Patient 22	F	47	NA	NA	CS	Ropinirole	Yes	N/A	Normal	N/A	Stopped ropinirole
Foley et al[12]	Patient 23	M	36	NA	NA	HS + CS + PG	Ropinirole	N/A	N/A	Normal	N/A	Reduced ropinirole
Foley et al[12]	Patient 24	F	50	NA	NA	CS	Ropinirole	Yes	N/A	Normal	N/A	N/A
Foley et al[12]	Patient 25	M	60	NA	NA	HS	Rotigotine	Yes	N/A	Normal	N/A	N/A
El Otmani et al[13]	Patient 26	M	37	40	3	HS	Pramipexole	N/A	N/A	N/A	No	Reduced pramipexole, added clozaping
El Otmani et al[13]	Patient 27	M	40	44	4	Punding	Piribedil	N/A	N/A	N/A	No	Reduced piribedil, added quetiapine
This study	Patient 28	M	60	69	9	BE+HS	Pramipexole	Yes	No	Mild bilateral frnto-remporal atrophy	Yes	Reduced pramipexole, added quetiapine

PD: Parkinson’s disease; OS: Othello syndrome; ICDs: Impulse control disorders; M: Male; F: Female; N/A: Not applicable; PG: Pathological gambling; HS: Hypersexuality; BE: Binge eating; DDS: Dopamine dysregulation syndrome; CS: Compulsive shopping.