Ren Y, Zhang J, Zhang JD, Xu JZ. Efficacy of digital breast tomosynthesis combined with magnetic resonance imaging in the diagnosis of early breast cancer. World J Clin Cases 2022; 10(28): 10042-10052 [PMID: 36246806 DOI: 10.12998/wjcc.v10.i28.10042]
Corresponding Author of This Article
Jian-Zhong Xu, Doctor, Chief Physician, Department of Breast Surgery, Changzhi People's Hospital Affiliated to Shanxi Medical University, No. 502 Changxing Zhong Road, Changzhi 046000, Shanxi Province, China. xjzzhuren@163.com
Research Domain of This Article
Surgery
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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World J Clin Cases. Oct 6, 2022; 10(28): 10042-10052 Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10042
Table 1 Pathological results of breast cancer group and benign group
Pathological results
No. of cases
Composition ratio (%)
Breast cancer patient
110
100.00
Invasive ductal carcinoma
66
60.00
Ductal carcinoma in situ
22
20.00
Lobular carcinoma in situ
13
11.82
Other types
9
8.18
Patients with benign breast tumors
110
100.00
Breast fibroma
55
50.00
Breast disease
27
24.55
Cystic hyperplasia of breast
14
12.73
Granulomatous lobular mastitis
8
7.27
Other types
6
5.45
Table 2 Matches four tables
DBT
Malignant
Benign
Total
Pathology
Malignant
81
29
110
Benign
17
93
110
Total
98
122
220
MRI
Pathology
Malignant
93
17
110
16
94
110
Benign
Total
109
111
220
MRI + DBT
Pathology
Malignant
107
3
110
Benign
7
103
110
Total
114
106
220
Table 3 The value of magnetic resonance imaging and digital breast tomosynthesis in differential diagnosis of breast benign and malignant diseases
Inspection method
Sensitivity
Specificity
Missed diagnosis rate
Misdiagnosis rate
AUC
DBT
73.64%
84.55%
26.36%
15.45%
0.791
MRI
84.55%
85.45%
15.45%
14.55%
0.850
DBT + MRI
97.27%
93.64%
2.73%
6.36%
0.955
Table 4 Comparison of general data between the breast-conserving group and the modified radical treatment group
Group
Breast-conserving group
Modified radical cure group
t/χ2
P value
n
69
41
Age (yr)
37.1 ± 7.1
39.2 ± 6.8
-1.523
0.131
BMI (kg/m2)
23.9 ± 1.9
23.2 ± 1.7
1.941
0.055
Affected side distribution, n (%)
Left side
34 (49.28)
25 (60.98)
1.416
0.243
Right side
35 (50.72)
16 (39.02)
Lesion diameter (cm)
2.18 ± 0.68
2.34 ± 0.70
-1.18
0.24
Pathology type
Invasive ductal carcinoma
43 (62.32)
23 (56.1)
2.171
0.538
Ductal carcinoma in situ
15 (21.74)
7 (17.07)
Lobular carcinoma in situ
6 (8.70)
7 (17.07)
Other types
5 (7.25)
4 (9.76)
Table 5 Comparison of perioperative indexes between the breast-conserving group and the modified radical treatment group (mean ± SD)
Group
n
Surgical bleeding (mL)
Operation time (min)
Hospital stay (d)
Breast-conserving group
69
66.2 ± 15.8
143.8 ± 24.1
9.5 ± 2.2
Modified radical cure group
41
106.7 ± 19.6
185.5 ± 28.0
13.7 ± 2.8
t
-11.869
-8.256
-8.731
P value
0.000
0.000
0.000
Table 6 Comparison of postoperative cosmetic effects between breast-conserving group and modified radical treatment group, n (%)
Group
n
Excellent
Good
Error
Breast-conserving group
69
58 (84.06)
11 (15.94)
0 (0.00)
Modified radical cure group
41
8 (19.51)
22 (53.66)
11 (26.83)
Z
-6.921
P value
0.000
Table 7 Comparison of quality of life between breast-conserving group and modified radical treatment group (mean ± SD)
Group
n
Preoperative
3 mo after surgery
t
P value
Breast-conserving group
69
81.03 ± 6.82
75.46 ± 8.14
3.850
0.000
Modified radical cure group
41
83.26 ± 7.24
70.04 ± 8.65
8.604
0.000
t
-1.621
3.299
P value
0.108
0.001
Citation: Ren Y, Zhang J, Zhang JD, Xu JZ. Efficacy of digital breast tomosynthesis combined with magnetic resonance imaging in the diagnosis of early breast cancer. World J Clin Cases 2022; 10(28): 10042-10052