Cytokine release syndrome complicated with rhabdomyolysis after chimeric antigen receptor T-cell therapy: A case report

Table 1 Clinical observations

	IL-6 (0-5 pg/mL)	Ferritin (13-150 ng/mL)	Creatine kinase (40-200 U/L)	Myoglobin (0-118 ng/mL)	LDH (120-250 U/L)	AST (13-35 U/L)	ALT (7-40U/L)	Cr (49-90 μmol/L)	BUN (2.8-7.6 mmol/L)
day1	8	1561	13		243	20	25	32	3
day2	21	1444	179		216	26	29	34	2
day3	289	1597	99		201	35	46	28	2
day4	499	1688	190		171	29	41	35	2
day5	3983	9673	103		238	61	85	41	1
day6	16745	16459	522		428	76	80	39	1
day7	33561	37968	512		446	174	99	45	4
day8	61369	> 40000	64941	22050	6948	1085	194	96	16
day9	10508	> 40000	35500	1170	4713	830	135	102	19
day10	2141	> 40000	27887	814	4941	701	143	118	9
day11	1024	> 40000	13804	667	3799	513	113	52	9
day12	513	> 40000	12804	173	4140	453	129	57	13
day13	400	> 40000	9489	89	3468	246	111	48	12
day14	386	> 40000	7195	64	3186	288	118	41	9
day15	238	38707	4720	31	2735	301	136	27	7
day16	152	21939	2678	24	2182	349	182	21	7
day17	81	15533	1395		2032	447	234	26	6
day18	41	7437	774		1746	164	148	25	4

IL: Interleukin; LDH: Lactate dehydrogenase; AST: Alaninetransaminase; ALT: Alaninetransaminase; Cr: Creatinine; BUN: Blood urea nitrogen.