Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit

Table 1 Analysis of potential factors influencing delirium in patients admitted to neurosurgical intensive care unit

Relative factors	Delirium group, n = 25	Observation group, n = 95	t/χ2 value	P value
Sex			0.135	0.804
Male	19	72
Female	6	23
Age in yr, mean ± SD	54.34 ± 11.09	55.40 ± 10.93	0.101	0.845
GCS score			13.033	0.001
≥ 8	12	70
5-8	13	25
Administration more than 3 medicines	18	65	3.024	0.052
Comorbid cerebral concussion	17	34	10.098	0.001
Comorbid cerebral contusion	15	28	9.075	0.001
Comorbid hypoxemia	17	35	7.865	0.001
Comorbid ventricular compression	16	27	12.096	0.001
Frontal lobe injury	18	30	9.763	0.001

GCS: Glasgow coma scale; SD: Standard deviation.

Table 2 Variate score setting for the logistic analysis

Variates	Score setting
GCS	1 indicated GCS score ≥ 8; 0 indicated GCS score between 5 and 8
Comorbid cerebral concussion	1 indicated presence of the comorbidity; 0 indicated absence of the comorbidity
Comorbid cerebral contusion	1 indicated presence of the comorbidity; 0 indicated absence of the comorbidity
Comorbid hypoxemia	1 indicated presence of the comorbidity; 0 indicated absence of the comorbidity
Comorbid ventricular compression	1 indicated presence of the comorbidity; 0 indicated absence of the comorbidity
Frontal lobe injury	1 indicated frontal lobe injury; 0 indicated injury of other sites of the brain

GCS: Glasgow coma scale.

Table 3 Multivariate logistic regression analysis of risk factors for the onset of delirium in patients with brain injury admitted to the neurosurgical intensive care unit

Variates	Β value	SE value	Wald χ2 value	P value	OR value	95%CI
GCS score	0.221	0.126	7.531	0.001	1.201	1.085-1.452
Comorbid cerebral concussion	0.189	0.223	6.542	0.001	1.154	1.058-1.503
Comorbid cerebral contusion	0.287	0.103	8.032	0.001	1.302	1.123-1.651
Comorbid hypoxemia	0.212	0.139	7.093	0.001	1.189	1.072-1.440
Comorbid ventricular compression	0.190	0.189	6.734	0.001	1.172	1.065-1.542
Frontal lobe injury	0.271	0.098	7.689	0.001	1.233	1.110-1.722

CI: Confidence interval; GCS: Glasgow coma scale; OR: Odds ratio.