Retrospective Study
Copyright ©The Author(s) 2022.
World J Clin Cases. Jan 7, 2022; 10(1): 91-103
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.91
Table 1 Baseline demographic details and outcome parameters
Characteristic
Overall cohort
Age, yr (mean ± SD)40 ± 13.6
Sex (%)
Males64.5
Females35.5
Etiology, n (%)
Alcohol79 (51)
Gallstones63 (40.6)
ERCP6 (3.9)
Idiopathic5 (3.2)
Hyperparathyroidism2 (1.3)
Co-morbidities, n (%)32
Diabetes mellitus19 (59.4)
Hypertension21 (65.6)
Coronary artery disease8 (25)
Chronic obstructive airway disease14 (43.7)
Obesity, n (%)18 (11.6%)
Severity, n (%)
Moderately severe72 (46.4)
Severe83 (53.5)
Pain to PCD interval, d (median)24
Site of collection, n (%)
Lesser sac94 (62.6)
Paracolic gutter28 (18.7)
Lesser sac and paracolic gutter16 (10.7)
Perisplenic4 (2.7)
Perihepatic3 (2)
Pelvic5 (3.3)
Infected necrosis, n (%)75 (36.7)
Organ failure, n (%)100 (64.5)
Length of hospital stay, d (mean ± SD)22 ± 19.3
Length of ICU stay, d (mean ± SD)6.1 ± 10.1
Surgery, n (%)24 (15.4)
Endoscopic drainage, n (%)7 (4.5)
Mortality, n (%)32 (20.6)
Table 2 Group statistics
Parameters
Overall cohort (n = 155)
Characteristics
Compared variable
Group I
Group II
P value

Number
109
46

Pain to PCD intervalMean39.854.10.249
Site of collection (%)Lesser sac64.252.20.464
Paracolic16.521.7
Lesser sac + paracolic118.7
ProcalcitoninMean3.25.40.331
Collection sizeMean11.411.50.974
Catheter size< 12F2380.598
> 12F8638
RAC severityModerately severe6211< 0.001
Severe4735
Infected necrosisNo71270.447
Yes3819
Organ failureNo43110.076
Yes6634
Table 3 Serial white blood cell count and neutrophil-lymphocyte ratio
Day
n
Median
IQR (25%-75%)
WBC
015514.99.9-20.7
111012.38.9-17.4
215111.68.3-17.6
310212.48.9-16.2
NLR
01408.25.2-14.1
1887.24.4-12
21366.44.1-11.9
3896.63.8-12.1
Table 4 Area under the curve for serial white blood cell count and neutrophil-lymphocyte ratio for differentiating responders from non-responders to percutaneous catheter drainage
Time point
WBC
NLR
Baseline (0)0.5080.401
24 h (1)0.6020.682
48 h (2)0.4680.407
72 h (3)0.4160.427