Vancomycin lavage for the incidence of acute surgical site infection following primary total hip arthroplasty and total knee arthroplasty

Table 1 Summary of the demographic data

Risk factor	Group 1 (n = 1018)	Group 2 (n = 1175)	P value
Sex, male (%)	46.95	48.09	0.5971
Age (mean ± SD), yr	59.59 ± 10.25	59.98 ± 10.38	0.3702
BMI (mean ± SD), kg/m2	27.50 ± 4.67	27.83 ± 4.82	0.1022
Antibiotic-loaded cement usage (%)	18.96	20.26	0.4461
Indication for primary TJA (%)
Osteoarthritis	81.34	80.85	0.7341
Avascular necrosis	4.91	4.34	0.5251
Inflammatory	2.95	2.13	0.2211
Other	10.80	12.68	0.1751

¹Pearson χ² test.

²t-test.

Group 1: Irrigation with normal saline; Group 2: Irrigation with vancomycin solution (1000 mg/L; 2 L); the values are presented as numbers (%) or means ± SD. BMI: Body mass index; TJA: Total joint arthroplasty.

Table 2 Incidence of acute surgical site infection, n (%)

Risk factor	Group 1 (n = 1018)	Group 2 (n = 1175)	P value
Superficial infection rate	6 (0.59)	1 (0.09)	0.0371
Deep infection rate	19 (1.86)	0 (0)	< 0.0011
Overall infection rate	25 (2.46)	1 (0.09)	< 0.0011

¹Pearson χ² test.

Group 1: Irrigation with normal saline. Group 2: Irrigation with vancomycin.