Cerebral venous sinus thrombosis in pregnancy: A case report

Table 1 Summary of reported cases of cerebral venous thrombosis in pregnant women treated with mechanical thrombectomy

Ref.	Age	Risk factors	Treatment	Results of post-intervention CTA/DSA	Maternal outcome	Fetal outcome	Complications
Kourtopoulos et al[12], 1994	18	Pregnancy	Open thrombectomy, thrombolysis, heparin + actilyse	NA	mRS = 5 after 3 mo	Healthy	Intracranial hemorrhage
Chow et al[13], 2000	21	Pregnancy, anti-phospholipid antibodies	Heparin, rheolytic thrombectomy, urokinase	Partial restoration of flow	mRS = 0 after 6 mo	NA	None
Ou et al[14], 2003	29	Pregnancy, ovarian hyperstimulation syndrome	Local thrombolysis (urokinase), mechanical thrombectomy, LMWH	Partial restoration of flow	mRS = 2 at discharge	Healthy	None
Falavigna et al[15], 2006	24	Pregnancy	Mechanical lysis + abciximab	Complete restoration of flow	mRS = 0 after 12 mo	Healthy	Intracranial hemorrhage
Li et al[16], 2013	32	Pregnancy, mastoiditis	Mechanical thrombectomy combined with urokinase	NA	mRS = 2 at discharge	NA	None
Li et al[16], 2013	32	Antithrombin III deficiency, pregnancy	Mechanical thrombectomy combined with urokinase	NA	death	NA	None
Li et al[16], 2013	26	Pregnancy	Mechanical thrombectomy combined with urokinase	NA	mRS = 0 at discharge	NA	None
Mokin et al[17], 2015	33	Pregnancy	Heparin, penumbra aspiration catheter and separator	Complete restoration of flow	mRS = 2 at discharge	NA	None
Mokin et al[17], 2015	19	Pregnancy	Heparin, AngioJet	Partial restoration of flow	mRS = 5 at discharge	NA	None
King et al[18], 2016	20	Pregnancy, antithrombin III deficiency	Heparin, mechanical thrombectomy (failed), catheter-directed tPA, heparin + argatroban	Partial restoration of flow	mRS = 2 at discharge	Healthy	None
Serna Candel et al[19], 2019	34	Pregnancy, Heterozygous factor V Leiden mutation	LMWH, aspiration thrombectomy (failed), balloon angioplasty (failed), acetylsalicylic acid, eptifibatide, ticagrelor	Partial restoration of flow	mRS = 2 at discharge	Healthy	None
Our case	29	Pregnancy, antithrombin III deficiency	LMWH, mechanical thrombectomy	Partial restoration of flow	mRS = 1 after 3 mo	Miscarriage	None

CVT: Cerebral venous thrombosis; CTA: Computed tomographic angiogram; DSA: Digital subtraction angiogram; NA: Not available; mRS: Modified Rankin Scale; LMWH: Low-molecular weight heparin; tPA: Tissue plasminogen activator.