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©The Author(s) 2022.
World J Clin Cases. Jan 7, 2022; 10(1): 260-267
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.260
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.260
Table 1 Status of biomarkers before neoadjuvant chemotherapy and after neoadjuvant chemotherapy
| Ref. | Year | Total patients (n) | Frequency of ER alternation, n (%) | Frequency of PR alternation, n (%) | Frequency of Her-2 alternation, n (%) | Frequency of Ki-67 alternation, n (%) | ||||||||||||
| P × P | P × N | N × P | N × N | P × P | P × N | N × P | N × N | P × P | P × N | N × P | N × N | P × P | P × N | N × P | N × N | |||
| Li et al[12] | 2019 | 565 | 229 (40.5) | 48 (8.5) | 53 (9.4) | 235 (41.6) | 191 (33.8) | 76 (13.5) | 53 (9.4) | 245 (43.4) | 439 (39.7) | 117 (10.6) | 13 (1.2) | 536 (48.5) | NA | NA | NA | NA |
| Peng et al[16] | 2019 | 112 | 56 (50.0) | 18 (16.1) | 7 (6.2) | 31 (27.7) | 32 (28.6) | 22 (19.6) | 10 (9.0) | 48 (42.9) | 30 (27.8) | 17 (15.2) | 6 (5.3) | 59 (52.7) | 43 (38.4) | 42 (37.5) | 3 (2.7) | 24 (21.4) |
| Ahn et al[2] | 2018 | 442 | 305 (69.0) | 10 (2.3) | 8 (1.8) | 119 (26.9) | 201 (45.5) | 65 (14.7) | 15 (3.4) | 161 (36.4) | 109 (24.7) | 4 (0.9) | 11 (2.5) | 318 (71.9) | 113 (25.6) | 151 (34.2) | 12 (2.7) | 166 (37.6) |
| Yang et al[17] | 2018 | 231 | 173 (74.9) | NA | NA | 3 (1.3) | 158 (68.4) | NA | NA | 18 (7.8) | 26 (11.3) | NA | NA | 150 (64.9) | 128 (55.4) | NA | NA | 48 (20.8) |
| De La Cruz et al[18] | 2018 | 54 | 19 (35.2) | 2 (3.7) | 1 (1.9) | 9 (16.7) | NA | NA | NA | NA | 5 (9.6) | 1 (1.9) | 24 (44.4) | NA | NA | NA | NA | NA |
| Yoshida et al[19] | 2017 | 588 | NA | NA | NA | NA | NA | NA | NA | NA | 66 (11.2) | 33 (5.6) | 11 (1.9) | 478 (81.3) | NA | NA | NA | NA |
| Xian et al[20] | 2017 | 77 | NA | NA | 2 (3.0) | NA | NA | NA | 2 (3.0) | NA | NA | NA | 1 (1.0) | NA | NA | NA | NA | NA |
| Niikura et al[21] | 2016 | 16580/16515/16271 | 10474 (63.2) | 499 (3.0) | 519 (3.1) | 5088 (30.7) | 6735 (40.8) | 1545 (9.4) | 766 (4.6) | 7469 (45.9) | 2210 (13.6) | 601 (3.7) | 340 (2.1) | 9607 (59.0) | NA | NA | NA | NA |
| Gahlaut et al[22] | 2016 | 133 | NA | 7 (5.3) | 9 (6.8) | NA | NA | 13 (9.8) | 5 (3.8) | NA | NA | 5 (3.8) | 2 (1.5) | NA | NA | NA | NA | NA |
| Lim et al[23] | 2016 | 290 | 189 (65.2) | 23 (7.9) | 29 (10.0) | 49 (16.9) | NA | NA | NA | NA | 65 (22.4) | 17 (5.9) | 0 (0.0) | 208 (71.7) | NA | NA | NA | NA |
| Parinyanitikul et al[10] | 2015 | 398 | 188 (47.2) | 23 (5.8) | 39 (9.8) | 148 (37.2) | 105 (26.4) | 57 (14.3) | 28 (7.0) | 207 (52.0) | 43 (10.8) | 29 (7.3) | 11 (2.8) | 308 (77.4) | NA | NA | NA | NA |
| Zhou et al[24] | 2015 | 107 | 66 (61.7) | 11 (10.3) | 4 (3.7) | 31 (29.0) | 50 (46.7) | 13 (12.1) | 13 (12.1) | 31 (29.0) | 39 (36.4) | 3 (2.8) | 2 (1.9) | 63 (58.9) | NA | NA | NA | NA |
| Jin et al[25] | 2015 | 423 | 202 (47.8) | 55 (13.0) | 23 (5.4) | 143 (33.8) | NA | NA | NA | NA | 55 (13.0) | 27 (6.4) | 13 (3.1) | 328 (77.5) | NA | NA | NA | NA |
| Tan et al[26] | 2014 | 267 | 87 (32.6) | 57 (21.3) | 27 (10.1) | 123 (46.1) | 78 (29.2) | 33 (12.4) | 21 (7.9) | 135 (50.6) | NA | NA | NA | NA | NA | NA | NA | NA |
| Yang et al[27] | 2013 | 113 | NA | 6 (5.3) | 8 (7.1) | NA | NA | 8 (7.1) | 10 (8.8) | NA | NA | 1 (0.9) | 1 (0.9) | NA | NA | NA | NA | NA |
| Cockburn et al[28] | 2013 | 133 | 67 (50.4) | 11 (8.3) | 1 (0.8) | 54 (40.6) | 40 (30.1) | 16 (12.0) | 8 (6.0) | 69 (51.9) | 24 (18.0) | 9 (6.8) | 7 (5.3) | 93 (69.9) | NA | NA | NA | NA |
| Lee et al[29] | 2013 | 120 | 58 (48.3) | 11 (9.2) | 4 (3.3) | 47 (39.2) | 26 (21.7) | 19 (15.8) | 3 (2.5) | 72 (60.0) | 18 (16.8) | 6 (5.6) | 5 (4.7) | 78 (72.9) | NA | NA | NA | NA |
| Dede et al[30] | 2013 | 63 | 29 (46.0) | 2 (3.2) | 0 (0.0) | 4 (6.3) | 17 (27.0) | 7 (11.1) | 3 (4.8) | 6 (9.5) | NA | NA | NA | NA | NA | NA | NA | NA |
| Kumaki et al[31] | 2011 | 53 | 30 (56.7) | 3 (5.7) | 2 (3.8) | 18 (34.0) | 15 (28.3) | 4 (7.5) | 3 (5.7) | 31 (58.5) | 9 (18.4) | 5 (10.2) | 0 (0.0) | 35 (71.4) | NA | NA | NA | NA |
- Citation: Wang L, Jiang Q, He MY, Shen P. HER2 changes to positive after neoadjuvant chemotherapy in breast cancer: A case report and literature review . World J Clin Cases 2022; 10(1): 260-267
- URL: https://www.wjgnet.com/2307-8960/full/v10/i1/260.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v10.i1.260