Retrospective Study
Copyright ©The Author(s) 2022.
World J Clin Cases. Jan 7, 2022; 10(1): 143-154
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.143
Table 1 Clinical characteristics and laboratory tests of permanent and latent right-to-left shunt in patent foramen ovale-related cryptogenic stroke patients and the normal control group
Permanent RLS (n = 68)
Latent RLS (n = 43)
Normal control group (n = 33)
P value
Age (SD)46.25 (11.54)42.26 (11.95)45.39 (13.57)0.161
Male (%)37 (54.41)28 (65.12)22 (66.67)0.375
Blood pressure
Systolic pressure (SD)129.68 (16.23)130.67 (19.25)128.97 (15.05)0.988
Diastolic pressure (SD)81.12 (11.46)82.42 (14.31)77.73 (10.49)0.386
Smoking (%)11 (16.18)13 (30.23)12 (36.36)0.057
Alcohol intake (%)5 (7.35)7 (16.28)7 (21.21)0.120
BMI (SD)24.40 (1.25)24.55 (1.29)24.84 (1.25)0.180
Previous stroke history (%)10 (14.71)7 (16.28)0 (0)0.055
Total cholesterol (SD)4.24 (0.85)4.25 (1.07)4.50 (0.92)0.390
High-density cholesterol(SD)1.21 (0.29)1.11 (0.24)1.27 (0.32)0.082
Low-density cholesterol(SD)2.44 (0.78)2.56 (0.93)2.65 (0.82)0.418
Triglyceride (SD)1.35 (0.64)1.37 (0.66)1.43 (0.51)0.502
Blood glucose (SD)5.08 (1.27)4.94 (0.83)5.22 (1.20)0.728
RBC (SD)4.63 (0.46)4.70 (0.58)4.64 (0.48)0.795
Platelet (SD)220.29 (53.28)216.02 (78.30)237.0 (55.83)0.061
Fibrinogen (SD)2.72 (0.69)2.99 (1.46)2.54 (0.58)0.524
D-dimer (SD)0.48 (0.35)0.47 (0.32)0.41 (0.32)0.428
APTT (SD)26.61 (4.47)26.79 (5.72)25.85 (3.71)0.621
WBC (SD)7.12 (2.24)6.67 (1.86)6.99 (1.55)0.540
hs-CRP (SD)2.63 (3.98)2.65 (3.50)1.38 (1.24)0.619
ESR (SD)10.54 (8.70)9.47 (6.95)8.48 (4.49)0.608
BUA (SD)300.20 (99.11)319.22 (66.32)311.93 (58.76)0.068
APTT: Activated partial thromboplastin time; BMI: Body mass index; BUA: Blood uric acid; ESR: Erythrocyte sedimentation rate; hs-CRP: Hypersensitive C-reactive protein; RBC: Red blood cell; RLS: Right-to-left shunt; SD: Standard deviation; WBC: White blood cell.