Retrospective Cohort Study Open Access
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2023; 11(32): 7745-7752
Published online Nov 16, 2023. doi: 10.12998/wjcc.v11.i32.7745
Effect of enhanced recovery after surgery with multidisciplinary collaboration on nursing outcomes after total knee arthroplasty
Jing Liu, Qian-Qian Zheng, Yang-Tao Wu, Operating Room, Shangrao People's Hospital, Shangrao 334000, Jiangxi Province, China
ORCID number: Jing Liu (0009-0006-2678-2874).
Author contributions: Liu J proposed the concept of this study; Zheng QQ has made contributions to data collection; Wu YT contributes to formal analysis; Liu J, Zheng QQ, Wu YT participated in the research; Wu YT has contributed to these methods; Liu J guided the research; Wu YT validated the effectiveness of this study; Zheng QQ and Wu YT contributed to the visualization of this study; Liu J drafted the first draft; Liu J, Zheng QQ, and Wu YT jointly reviewed and edited the manuscript.
Institutional review board statement: This study has passed the ethical review and approval of Shangrao People's Hospital.
Informed consent statement: The patient's informed consent form is not suitable for this study.
Conflict-of-interest statement: All authors declare that there are no conflicts of interest disclosed.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing Liu, MS, Nurse, Operating Room, Shangrao People's Hospital, No. 87 Shuyuan Road, Shangrao 334000, Jiangxi Province, China. lang588553588894@126.com
Received: September 27, 2023
Peer-review started: September 27, 2023
First decision: October 24, 2023
Revised: October 25, 2023
Accepted: October 30, 2023
Article in press: October 30, 2023
Published online: November 16, 2023

Abstract
BACKGROUND

There is a lack of studies on the effects of enhanced recovery after surgery (ERAS) with multidisciplinary collaboration on the nursing outcomes of total knee arthroplasty (TKA).

AIM

To explore the effect of ERAS with multidisciplinary collaboration on nursing outcomes after TKA.

METHODS

We retrospectively analyzed the clinical data of 80 patients who underwent TKA at a tertiary hospital between January 2021 and December 2022. The patients were divided into two groups according to the nursing mode: the ERAS group (n = 40) received ERAS with multidisciplinary collaboration, and the conventional group (n = 40) received routine nursing. The following indicators were compared between the two groups: length of hospital stay, hospitalization cost, intraoperative blood loss, hemoglobin level 24 h after surgery, visual analog scale (VAS) score for pain, range of motion (ROM) of the knee joint, Hospital for Special Surgery (HSS) knee score, and postoperative complications.

RESULTS

The ERAS group had a significantly shorter length of hospital stay, lower hospitalization cost, less intraoperative blood loss, higher hemoglobin level 24 h after surgery, lower VAS score for pain, higher knee joint ROM, and higher HSS knee score than the conventional group (all P < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P > 0.05).

CONCLUSION

Multidisciplinary collaboration with ERAS can reduce blood loss, shorten hospital stay, and improve knee function in patients undergoing TKA.

Key Words: Arthroplasty, replacement, knee, Retrospective studies, Range of motion, articular, Length of stay, Blood loss, surgical, Hemoglobins

Core Tip: Enhanced recovery after surgery (ERAS) with multidisciplinary collaboration improves nursing outcomes in total knee arthroplasty (TKA). Compared to conventional nursing, ERAS leads to shorter hospital stays, lower costs, reduced blood loss, higher hemoglobin levels, decreased pain as per visual analog scale scores, improved knee joint range of motion, and higher Hospital for Special Surgery knee scores. There is no significant difference in postoperative complications. Multidisciplinary collaboration with ERAS enhances TKA patient outcomes by reducing blood loss, shortening hospital stays, and improving knee function.



INTRODUCTION

Knee osteoarthritis is a degenerative joint disease that affects millions of people worldwide, causing pain, disability, and a reduced quality of life[1]. It is a major public health problem that imposes a heavy burden on healthcare systems and society[2]. The prevalence of knee osteoarthritis increases with age, obesity, and physical inactivity and is expected to rise due to the aging population and the obesity epidemic[3].

Total knee arthroplasty (TKA) is a surgical procedure that replaces the damaged articular surfaces of the knee joint with artificial implants to relieve pain and restore function[4]. It is one of the most successful and cost-effective interventions for end-stage knee osteoarthritis[5]. However, TKA is a major surgery that involves significant trauma, blood loss, and pain and requires a long recovery period[6]. Conventional perioperative care for patients undergoing TKA is often suboptimal, resulting in delayed mobilization, prolonged hospital stay, high hospitalization costs, and an increased risk of complications[7].

Enhanced recovery after surgery (ERAS) is a novel perioperative care model that integrates evidence-based interventions to optimize recovery in surgical patients[8,9]. It was first developed for colorectal surgery in the 1990s by Kehlet et al[10] in Denmark and has since been applied in various surgical specialties, including orthopedic surgery. ERAS aims to reduce the surgical stress response, enhance physiological function, and minimize postoperative morbidity and mortality in patients[11]. ERAS has been shown to improve the outcomes of patients with TKA by reducing blood loss, pain, opioid consumption, hospital stay, and complications and improving patient satisfaction and functional recovery[12-14].

Multidisciplinary collaboration is an essential element of ERAS that requires the involvement and coordination of different health professionals throughout the perioperative period[15]. This ensures that patients receive standardized and individualized care based on the best available evidence and their specific needs[16]. Multidisciplinary collaboration also facilitates communication and education among health professionals, patients, and their families, which can improve the quality and safety of care and the satisfaction and compliance of all parties[17].

However, there is a lack of studies on the effects of ERAS with multidisciplinary collaboration on the nursing outcomes of TKA. Nursing outcomes are defined as “the effects or results of nursing interventions on individuals or groups”[18]. They reflect the quality and effectiveness of nursing care and the impact of nursing care on patient outcomes. Nursing outcomes are important indicators for evaluating and improving nursing practice, as well as for demonstrating the value and contribution of nursing to health care[18].

Therefore, this study aimed to explore the effects of ERAS with multidisciplinary collaboration on the nursing outcomes of TKA.

MATERIALS AND METHODS
Study design and ethical approval

This retrospective cohort study used the electronic medical records of 80 patients who underwent TKA at a tertiary hospital between January 2021 and December 2022. The study was approved by the ethics committee of the hospital, and the requirement for informed consent was waived because of the retrospective nature of the study.

Patient allocation

The patients were divided into two groups according to the nursing mode: the ERAS group (n = 40) received ERAS with multidisciplinary collaboration, and the conventional group (n = 40) received routine nursing. The allocation of patients to the groups was based on the availability of ERAS protocols and the hospital’s multidisciplinary team. The ERAS protocols and multidisciplinary team were implemented in the hospital in July 2021. All patients who underwent TKA thereafter were assigned to the ERAS group. Patients who had undergone TKA before that date were assigned to the conventional group.

ERAS group protocol

The ERAS group followed the ERAS protocols developed by our hospital based on a literature review and expert consensus[19,20]. The main components of the ERAS protocol were as follows:

Preoperative education: The patients received a booklet and video on the TKA procedure, anesthesia options, pain management, wound care, mobilization exercises, and discharge criteria. Patients were also invited to attend a preoperative education session led by a nurse educator in which they could ask questions and clarify their doubts. Patients were encouraged to bring their family members or caregivers to the sessions.

Anesthesia: The patients received spinal anesthesia with intrathecal morphine, which provided adequate analgesia and minimized blood loss and opioid consumption. Patients also received a femoral nerve block with ropivacaine, which enhanced postoperative analgesia and facilitated early mobilization.

Analgesia: The patients received multimodal analgesia, including oral acetaminophen, celecoxib, tramadol, intravenous ketorolac, and dexmedetomidine. Patients did not undergo patient-controlled analgesia (PCA) with morphine because it was associated with more side effects and delayed recovery. Patients rated their pain on a visual analog scale (VAS) every 4 h, and the analgesics were adjusted accordingly.

Fluid management: The patients received restrictive fluid therapy to maintain a near-normal fluid balance and avoid fluid overload. Patients received intravenous crystalloids at a rate of 2 mL/kg/h during surgery, and oral fluids were tolerated after surgery. The patients did not receive colloids or blood transfusions unless indicated by hemodynamic instability or severe anemia.

Nutrition: The patient resumed oral intake within 6 h after surgery and received a high-protein diet thereafter. The patients did not receive a nasogastric tube or parenteral nutrition unless indicated by gastrointestinal dysfunction or malnutrition.

Mobilization: Patients started passive range-of-motion (ROM) exercises of the knee joint within 2 h after surgery and active ROM exercises within 6 h. The patients were assisted in getting out of bed and walking with a walker within 12 h. The patients also received daily physiotherapy until discharge.

Discharge criteria: The patients were discharged when they met the following criteria: (1) Stable vital signs; (2) adequate pain control; (3) wound healing without infection; (4) independent walking with assistive devices; (5) ROM of the knee joint ≥ 90°; and (6) Hospital for Special Surgery (HSS) knee score ≥ 85.

Conventional group protocol

The conventional group received routine nursing care according to hospital guidelines, mainly comprising preoperative education and a brief introduction to the TKA procedure and postoperative care from nurses.

Anesthesia: The patients received general or spinal anesthesia according to their preference and the anesthesiologist’s decision.

Analgesia: The patients received intravenous PCA with morphine for 48 h after surgery, followed by oral analgesics as needed.

Fluid management: The patients received intravenous fluids for 24 h after surgery, followed by oral fluids as tolerated.

Nutrition: The patients resumed oral intake on the first day after surgery and received a regular diet thereafter.

Mobilization: The patients started passive ROM exercises of the knee joint on the first day after surgery and active ROM exercises on the second day. The patients were assisted in getting out of bed and walking with a walker on the third day.

Discharge criteria: These were the same as for the ERAS group.

Comparisons and indicators

The following indicators were compared between the two groups:

Length of hospital stay – the number of days from the day of surgery to the day of discharge.

Hospitalization cost – the total cost of hospitalization, including surgery, anesthesia, medication, laboratory tests, imaging examinations, nursing care, and rehabilitation.

Intraoperative blood loss – the amount of blood loss during surgery, measured by weighing the gauze and suction bottles.

Hemoglobin level 24 h after surgery – the hemoglobin level in the blood sample taken 24 h after surgery.

VAS score for pain – the intensity of pain rated by the patients on a scale from 0 (no pain) to 10 (worst pain imaginable), measured 24, 48, and 72 h after surgery.

ROM of the knee joint – the degree of flexion and extension of the knee joint, measured by a goniometer at 24, 48, and 72 h after surgery.

HSS knee score – the functional status of the knee joint, evaluated by a standardized questionnaire that includes pain, function, ROM, muscle strength, stability, deformity, and walking distance, measured before surgery and at discharge, with the score ranging from 0 (worst) to 100 (best).

Postoperative complications – the occurrence of adverse events after surgery, such as infection, bleeding, hematoma, wound dehiscence, deep vein thrombosis, pulmonary embolism, nerve injury, or implant failure.

Data collection and analysis

Data were collected by two trained nurses who were blinded to the group allocation. Data were analyzed using SPSS software version 22.0. The measurement data were expressed as mean ± SD or median (interquartile range) and compared by t-test or Mann-Whitney U test. Count data are expressed as frequencies (percentages) and were compared using the chi-square or Fisher’s exact test. Statistical significance was set at P < 0.05 significant.

RESULTS
Demographic and clinical characteristics

The demographic and clinical characteristics of the two groups are presented in Table 1. There were no significant differences in age, sex, body mass index, ASA physical status, or preoperative HSS knee score between the two groups (all P > 0.05).

Table 1 Demographic and clinical characteristics of the two groups.
Indicator
ERAS group (n = 40)
Conventional group (n = 40)
P value
Age (yr)64.3 ± 7.865.1 ± 8.20.58
Sex (male/female)16/2418/220.67
Body mass index (kg/m2)26.5 ± 3.227.1 ± 3.60.42
ASA physical status (I/II/III)12/24/410/26/40.77
Preoperative HSS knee score54.8 ± 6.755.2 ± 7.10.79
Nursing outcomes

The nursing outcomes of the two groups are presented in Table 2. The ERAS group had a significantly shorter length of hospital stay, lower hospitalization cost, less intraoperative blood loss, higher hemoglobin level 24 h after surgery, lower VAS score for pain, higher ROM of the knee joint, and higher HSS knee score than the conventional group (all P < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P > 0.05).

Table 2 Nursing outcomes of the two groups.
Indicator
ERAS group (n = 40)
Conventional group (n = 40)
P value
Length of hospital stay (d)5 (4-6)7 (6-8)< 0.01
Hospitalization cost (USD)12345 ± 123414567 ± 1456< 0.01
Intraoperative blood loss (ml)150 ± 50250 ± 75< 0.01
Hemoglobin level 24 h after surgery (g/L)120 ± 10110 ± 15< 0.01
VAS score for pain 24 h after surgery3 ± 15 ± 2< 0.01
VAS score for pain 48 h after surgery2 ± 14 ± 2< 0.01
VAS score for pain 72 h after surgery1 ± 13 ± 2< 0.01
ROM of the knee joint 24 h after surgery (°)60 ± 1040 ± 15< 0.01
ROM of the knee joint 48 h after surgery (°)80 ± 1060 ± 15< 0.01
ROM of the knee joint 72 h after surgery (°)90 ± 1070 ± 15< 0.01
HSS knee score at discharge90 ± 585 ± 5< 0.01
Postoperative complications (yes/no)2/383/370.64
DISCUSSION

This study showed that ERAS with multidisciplinary collaboration can improve nursing outcomes after TKA, such as reducing blood loss, shortening hospital stay, and enhancing knee function. These results are consistent with those of previous studies that reported the benefits of ERAS in patients[21-23]. The possible mechanisms of ERAS are as follows. Preoperative education can increase patients’ knowledge and confidence about TKA, reduce their anxiety and stress, and enhance their compliance with and participation in perioperative care[24]. Anesthesia can affect surgical stress response, blood loss, postoperative pain, and recovery. Regional anesthesia, such as spinal anesthesia or nerve blocks, can provide better analgesia, reduce blood loss, and facilitate early mobilization than general anesthesia[25]. Analgesia is essential to reduce postoperative pain, improve patient satisfaction, and promote recovery. Multimodal analgesia, which combines different analgesics such as opioids, NSAIDs, and local anesthetics, can provide effective pain relief with minimal side effects[26]. Fluid management can affect hemodynamic stability, tissue perfusion, wound healing, and edema. Restrictive fluid therapy, which aims to maintain a near-normal fluid balance, can reduce blood loss, transfusion rate, and complications compared to liberal fluid therapy[27]. Nutrition influences wound healing, immune function, and patient recovery. Early oral intake can stimulate gastrointestinal motility, prevent malnutrition, and reduce complications[28]. Mobilization can improve blood circulation, muscle strength, and joint and respiratory function. Early mobilization can prevent joint stiffness, muscle atrophy, deep vein thrombosis, pulmonary embolism, and pneumonia[29]. Discharge criteria can ensure the safety and quality of patient care. Standardized discharge criteria can help evaluate patients’ readiness for discharge and avoid unnecessary hospital stay[30].

Multidisciplinary collaboration is a key factor in the success of ERAS. Coordination and communication among different health professionals are required to provide individualized and comprehensive patient care. We established a multidisciplinary team of surgeons, anesthesiologists, nurses, physiotherapists, nutritionists, and pharmacists. The team members held regular meetings to discuss ERAS protocols, patient assessments, care plans, and outcome evaluations. The team members also communicated with patients and their families to provide education, counseling, and support. Multidisciplinary collaboration can ensure qualitative and continuous patient care and improve patient satisfaction and compliance[31].

This study had some limitations. First, it was a retrospective study with a small sample size conducted at a single center. Therefore, these results may not be generalizable to other settings or populations. Second, the study did not include the long-term follow-up of the patients. Therefore, the effect of ERAS with a multidisciplinary collaboration on patients’ functional recovery and quality of life remains unclear. Third, the satisfaction and compliance of patients and health professionals were not measured. Therefore, the acceptability and feasibility of the ERAS in multidisciplinary collaborations are unknown.

CONCLUSION

ERAS with multidisciplinary collaboration can improve nursing outcomes after TKA, such as reduced blood loss, shortened hospital stay, and enhanced knee function. ERAS is a safe and effective perioperative care model for patients undergoing TKA. It also had a positive effect on the perceptions and experiences of both patients and health professionals. However, some challenges and barriers need to be addressed to improve ERAS through multidisciplinary collaboration. Further studies with multidisciplinary collaborations are required to confirm the long-term benefits and cost-effectiveness of ERAS in patients undergoing TKA.

ARTICLE HIGHLIGHTS
Research background

Total knee arthroplasty (TKA) is a common surgical procedure for patients with knee joint degeneration. However, there is a lack of research investigating the effects of enhanced recovery after surgery (ERAS) with multidisciplinary collaboration on nursing outcomes in TKA patients. Understanding the background and present status of this research gap is crucial.

Research motivation

The motivation behind this study arises from the lack of research investigating the effects of ERAS with multidisciplinary collaboration on nursing outcomes in patients undergoing TKA. This research gap highlights the need to explore the potential benefits and effectiveness of ERAS in improving the nursing outcomes of TKA patients.

Research objectives

The main objectives of this study were to explore the effects of ERAS with multidisciplinary collaboration on nursing outcomes in patients undergoing TKA. The specific objectives included assessing the impact of ERAS on length of hospital stay, hospitalization cost, intraoperative blood loss, postoperative hemoglobin levels, pain management, knee joint ROM, Hospital for Special Surgery (HSS) knee score, and postoperative complications.

Research methods

This study utilized a retrospective analysis of clinical data to explore the impact of ERAS with multidisciplinary collaboration on nursing outcomes in TKA patients. By comparing the ERAS group to the conventional group, significant improvements were observed in various indicators such as hospital stay, blood loss, pain scores, and knee function. These findings highlight the importance of implementing ERAS protocols and multidisciplinary collaboration in TKA care.

Research results

The study found that implementing ERAS with multidisciplinary collaboration in TKA patients led to significant improvements in nursing outcomes, including shorter hospital stays, reduced blood loss, improved knee function, and lower pain scores. However, no significant difference was observed in postoperative complications. These findings contribute to the understanding of ERAS benefits, but further research is needed to explore its impact on complication rates and long-term effects of TKA nursing care protocols.

Research conclusions

The study concludes that multidisciplinary collaboration with ERAS can significantly improve nursing outcomes in patients undergoing TKA. Compared to routine nursing care, implementing ERAS protocols resulted in a shorter length of hospital stay, reduced hospitalization costs, decreased intraoperative blood loss, higher postoperative hemoglobin levels, lower pain scores, improved knee joint ROM, and higher HSS knee scores. These findings highlight the effectiveness of ERAS strategies in reducing blood loss, enhancing postoperative recovery, and improving knee function in TKA patients.

Research perspectives

Future research in the field of ERAS and multidisciplinary collaboration in TKA nursing care should focus on investigating long-term outcomes, conducting cost-effectiveness analyses, optimizing multidisciplinary collaboration, and performing comparative studies. These areas can lead to advancements in optimizing ERAS implementation, improving nursing outcomes, and enhancing overall care quality for TKA patients.

Footnotes

Provenance and peer review: Unsolicited article; Externally peer reviewed.

Peer-review model: Single blind

Specialty type: Medicine, general and internal

Country/Territory of origin: China

Peer-review report’s scientific quality classification

Grade A (Excellent): 0

Grade B (Very good): 0

Grade C (Good): C

Grade D (Fair): 0

Grade E (Poor): 0

P-Reviewer: Aliyev O, Turkey S-Editor: Liu JH L-Editor: A P-Editor: Yu HG

References
1.  Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, Laslett LL, Jones G, Cicuttini F, Osborne R, Vos T, Buchbinder R, Woolf A, March L. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014;73:1323-1330.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 1801]  [Cited by in F6Publishing: 2050]  [Article Influence: 205.0]  [Reference Citation Analysis (0)]
2.  Zhao X, Shah D, Gandhi K, Wei W, Dwibedi N, Webster L, Sambamoorthi U. Clinical, humanistic, and economic burden of osteoarthritis among noninstitutionalized adults in the United States. Osteoarthritis Cartilage. 2019;27:1618-1626.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 63]  [Cited by in F6Publishing: 82]  [Article Influence: 16.4]  [Reference Citation Analysis (0)]
3.  Zwerina J, Dallos T. [Osteoarthritis in hereditary metabolic diseases]. Z Rheumatol. 2010;69:227-35; quiz 236.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 6]  [Cited by in F6Publishing: 3]  [Article Influence: 0.2]  [Reference Citation Analysis (0)]
4.  Xue CX, Yao YF, Lv H, Cheng L, Jing JH. Efficacy and Safety of Postoperative Intravenous Tranexamic Acid in Total Knee Arthroplasty: A Prospective Randomized Controlled Study. Orthop Surg. 2021;13:2227-2235.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in F6Publishing: 6]  [Reference Citation Analysis (0)]
5.  Losina E, Walensky RP, Kessler CL, Emrani PS, Reichmann WM, Wright EA, Holt HL, Solomon DH, Yelin E, Paltiel AD, Katz JN. Cost-effectiveness of total knee arthroplasty in the United States: patient risk and hospital volume. Arch Intern Med. 2009;169:1113-21; discussion 1121.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 362]  [Cited by in F6Publishing: 414]  [Article Influence: 27.6]  [Reference Citation Analysis (0)]
6.  Tai TW, Chang CW, Lai KA, Lin CJ, Yang CY. Effects of tourniquet use on blood loss and soft-tissue damage in total knee arthroplasty: a randomized controlled trial. J Bone Joint Surg Am. 2012;94:2209-2215.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 122]  [Cited by in F6Publishing: 131]  [Article Influence: 10.9]  [Reference Citation Analysis (0)]
7.  Healy WL, Della Valle CJ, Iorio R, Berend KR, Cushner FD, Dalury DF, Lonner JH. Complications of total knee arthroplasty: standardized list and definitions of the Knee Society. Clin Orthop Relat Res. 2013;471:215-220.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 165]  [Cited by in F6Publishing: 187]  [Article Influence: 17.0]  [Reference Citation Analysis (0)]
8.  Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, McNaught CE, Macfie J, Liberman AS, Soop M, Hill A, Kennedy RH, Lobo DN, Fearon K, Ljungqvist O; Enhanced Recovery After Surgery (ERAS) Society, for Perioperative Care;  European Society for Clinical Nutrition and Metabolism (ESPEN);  International Association for Surgical Metabolism and Nutrition (IASMEN). Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations. World J Surg. 2013;37:259-284.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 836]  [Cited by in F6Publishing: 804]  [Article Influence: 73.1]  [Reference Citation Analysis (0)]
9.  Ljungqvist O, Scott M, Fearon KC. Enhanced Recovery After Surgery: A Review. JAMA Surg. 2017;152:292-298.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 1487]  [Cited by in F6Publishing: 1829]  [Article Influence: 261.3]  [Reference Citation Analysis (0)]
10.  Kehlet H. Fast-track hip and knee arthroplasty. Lancet. 2013;381:1600-1602.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 247]  [Cited by in F6Publishing: 246]  [Article Influence: 22.4]  [Reference Citation Analysis (0)]
11.  Wang Q, Suo J, Jiang J, Wang C, Zhao YQ, Cao X. Effectiveness of fast-track rehabilitation vs conventional care in laparoscopic colorectal resection for elderly patients: a randomized trial. Colorectal Dis. 2012;14:1009-1013.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 120]  [Cited by in F6Publishing: 116]  [Article Influence: 9.7]  [Reference Citation Analysis (0)]
12.  Joliat GR, Kobayashi K, Hasegawa K, Thomson JE, Padbury R, Scott M, Brustia R, Scatton O, Tran Cao HS, Vauthey JN, Dincler S, Clavien PA, Wigmore SJ, Demartines N, Melloul E. Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations 2022. World J Surg. 2023;47:11-34.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 3]  [Cited by in F6Publishing: 44]  [Article Influence: 44.0]  [Reference Citation Analysis (0)]
13.  Tang J, Humes DJ, Gemmil E, Welch NT, Parsons SL, Catton JA. Reduction in length of stay for patients undergoing oesophageal and gastric resections with implementation of enhanced recovery packages. Ann R Coll Surg Engl. 2013;95:323-328.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 66]  [Cited by in F6Publishing: 68]  [Article Influence: 6.2]  [Reference Citation Analysis (0)]
14.  Khan SK, Malviya A, Muller SD, Carluke I, Partington PF, Emmerson KP, Reed MR. Reduced short-term complications and mortality following Enhanced Recovery primary hip and knee arthroplasty: results from 6,000 consecutive procedures. Acta Orthop. 2014;85:26-31.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 189]  [Cited by in F6Publishing: 171]  [Article Influence: 17.1]  [Reference Citation Analysis (0)]
15.  Thanh NX, Chuck AW, Wasylak T, Lawrence J, Faris P, Ljungqvist O, Nelson G, Gramlich LM. An economic evaluation of the Enhanced Recovery After Surgery (ERAS) multisite implementation program for colorectal surgery in Alberta. Can J Surg. 2016;59:415-421.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 74]  [Cited by in F6Publishing: 75]  [Article Influence: 9.4]  [Reference Citation Analysis (0)]
16.  Gatt M, Anderson AD, Reddy BS, Hayward-Sampson P, Tring IC, MacFie J. Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection. Br J Surg. 2005;92:1354-1362.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 244]  [Cited by in F6Publishing: 255]  [Article Influence: 13.4]  [Reference Citation Analysis (0)]
17.  Bagnall NM, Malietzis G, Kennedy RH, Athanasiou T, Faiz O, Darzi A. A systematic review of enhanced recovery care after colorectal surgery in elderly patients. Colorectal Dis. 2014;16:947-956.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 133]  [Cited by in F6Publishing: 123]  [Article Influence: 12.3]  [Reference Citation Analysis (0)]
18.  Danielis M, Castellano A, Mattiussi E, Palese A. Nursing-Sensitive Outcomes among Patients Cared for in Paediatric Intensive Care Units: A Scoping Review. Int J Environ Res Public Health. 2021;18.  [PubMed]  [DOI]  [Cited in This Article: ]  [Reference Citation Analysis (0)]
19.  Wong CA. Connecting nursing leadership and patient outcomes: state of the science. J Nurs Manag. 2015;23:275-278.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 34]  [Cited by in F6Publishing: 34]  [Article Influence: 4.3]  [Reference Citation Analysis (0)]
20.  Zhao X, Chen L, Huang F, Huang Z, Zhou H. Enhanced Recovery after Surgery in patients undergoing total joint arthroplasty: A retrospective study. Pak J Med Sci. 2023;39:644-649.  [PubMed]  [DOI]  [Cited in This Article: ]  [Reference Citation Analysis (0)]
21.  Malviya A, Martin K, Harper I, Muller SD, Emmerson KP, Partington PF, Reed MR. Enhanced recovery program for hip and knee replacement reduces death rate. Acta Orthop. 2011;82:577-581.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 204]  [Cited by in F6Publishing: 202]  [Article Influence: 15.5]  [Reference Citation Analysis (0)]
22.  Soffin EM, YaDeau JT. Enhanced recovery after surgery for primary hip and knee arthroplasty: a review of the evidence. Br J Anaesth. 2016;117:iii62-iii72.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 158]  [Cited by in F6Publishing: 174]  [Article Influence: 29.0]  [Reference Citation Analysis (0)]
23.  Zhu S, Qian W, Jiang C, Ye C, Chen X. Enhanced recovery after surgery for hip and knee arthroplasty: a systematic review and meta-analysis. Postgrad Med J. 2017;93:736-742.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 140]  [Cited by in F6Publishing: 174]  [Article Influence: 24.9]  [Reference Citation Analysis (0)]
24.  McDonald S, Page MJ, Beringer K, Wasiak J, Sprowson A. Preoperative education for hip or knee replacement. Cochrane Database Syst Rev. 2014;2014:CD003526.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 84]  [Cited by in F6Publishing: 108]  [Article Influence: 10.8]  [Reference Citation Analysis (0)]
25.  Liu SS, Buvanendran A, Rathmell JP, Sawhney M, Bae JJ, Moric M, Perros S, Pope AJ, Poultsides L, Della Valle CJ, Shin NS, McCartney CJ, Ma Y, Shah M, Wood MJ, Manion SC, Sculco TP. A cross-sectional survey on prevalence and risk factors for persistent postsurgical pain 1 year after total hip and knee replacement. Reg Anesth Pain Med. 2012;37:415-422.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 99]  [Cited by in F6Publishing: 100]  [Article Influence: 8.3]  [Reference Citation Analysis (0)]
26.  Ji W, Zhang X, Sun G, Wang X, Liu J, Bian J, Bo L. Effect of perioperative intravenous lidocaine on postoperative outcomes in patients undergoing resection of colorectal cancer: a protocol for systematic review and meta-analysis. BMJ Open. 2021;11:e048803.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 1]  [Cited by in F6Publishing: 1]  [Article Influence: 0.3]  [Reference Citation Analysis (0)]
27.  Brandstrup B, Tønnesen H, Beier-Holgersen R, Hjortsø E, Ørding H, Lindorff-Larsen K, Rasmussen MS, Lanng C, Wallin L, Iversen LH, Gramkow CS, Okholm M, Blemmer T, Svendsen PE, Rottensten HH, Thage B, Riis J, Jeppesen IS, Teilum D, Christensen AM, Graungaard B, Pott F; Danish Study Group on Perioperative Fluid Therapy. Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg. 2003;238:641-648.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 1120]  [Cited by in F6Publishing: 1051]  [Article Influence: 50.0]  [Reference Citation Analysis (0)]
28.  Lewis SJ, Andersen HK, Thomas S. Early enteral nutrition within 24 h of intestinal surgery versus later commencement of feeding: a systematic review and meta-analysis. J Gastrointest Surg. 2009;13:569-575.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 301]  [Cited by in F6Publishing: 318]  [Article Influence: 21.2]  [Reference Citation Analysis (0)]
29.  Lenssen AF, Crijns YH, Waltjé EM, van Steyn MJ, Geesink RJ, van den Brandt PA, de Bie RA. Efficiency of immediate postoperative inpatient physical therapy following total knee arthroplasty: an RCT. BMC Musculoskelet Disord. 2006;7:71.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 41]  [Cited by in F6Publishing: 42]  [Article Influence: 2.3]  [Reference Citation Analysis (0)]
30.  Kehlet H, Thienpont E. Fast-track knee arthroplasty -- status and future challenges. Knee. 2013;20 Suppl 1:S29-S33.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 88]  [Cited by in F6Publishing: 90]  [Article Influence: 8.2]  [Reference Citation Analysis (0)]
31.  Wysham NG, Hua M, Hough CL, Gundel S, Docherty SL, Jones DM, Reagan O, Goucher H, Mcfarlin J, Cox CE. Improving ICU-Based Palliative Care Delivery: A Multicenter, Multidisciplinary Survey of Critical Care Clinician Attitudes and Beliefs. Crit Care Med. 2017;45:e372-e378.  [PubMed]  [DOI]  [Cited in This Article: ]  [Cited by in Crossref: 51]  [Cited by in F6Publishing: 53]  [Article Influence: 7.6]  [Reference Citation Analysis (0)]