Case Report
Copyright ©The Author(s) 2021.
World J Clin Cases. Feb 26, 2021; 9(6): 1416-1423
Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1416
Figure 1
Figure 1 Plain radiography at first medical examination. Radiograph shows an osteolytic lesion of the right tibia.
Figure 2
Figure 2 Computed tomography images of the tibia. A: Axial computed tomography image showing the purely osteolytic lesion of the right tibia; B and C: Coronal computed tomography images showing a similar round cystic bone defect area with a sclerotic margin, the range was about 10 mm × 9 mm × 18 mm, the adjacent bone cortex was obviously thickened, periosteal reaction was visible, and no definite swelling was found in the surrounding soft tissue.
Figure 3
Figure 3 Magnetic resonance images of the tibia. Magnetic resonance images showing a sharply defined unclear lesion and high heterogeneous signal intensity on T1-weighted images and T2-weighted images.
Figure 4
Figure 4 The biopsy confirms osseous Rosai-Dorfman Disease, immunohistochemistry result: CD207 (+), S-100 (+), CD1a (-), CD68 (+), CD163 (+), Ki67 (inflammatory cell +), anaplastic lymphoma kinase (-), CD30 (-), CD5 (+), and CD20 (+); special staining: Hexamine silver (-). The orange arrow shows emperipolesis phenomenon.